250 lines
14 KiB
Plaintext
250 lines
14 KiB
Plaintext
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Gene,Alteration,Oncogenic,Mutation_Effect,Citations
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CDK6,Amplification,Oncogenic,Gain-of-function,4
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MCL1,Amplification,Oncogenic,Gain-of-function,4
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PDGFRA,Amplification,Oncogenic,Gain-of-function,4
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SRC,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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FGFR4,Amplification,Oncogenic,Gain-of-function,4
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ECSIT,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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EGFR,Amplification,Oncogenic,Gain-of-function,4
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HRAS,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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ERCC2,Amplification,Inconclusive,Inconclusive,4
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ATP1A1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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UBR5,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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PDGFRB,Amplification,Inconclusive,Inconclusive,4
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MYC,Amplification,Oncogenic,Gain-of-function,4
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CDK4,Amplification,Oncogenic,Gain-of-function,4
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RICTOR,Amplification,Oncogenic,Gain-of-function,4
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ALK,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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FGFR2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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PHF19,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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RAC1,Amplification,Likely Oncogenic,Gain-of-function,4
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CARD11,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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AXL,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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FGFR1,Amplification,Oncogenic,Gain-of-function,4
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PIK3R2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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KAT7,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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GLI1,Amplification,Oncogenic,Gain-of-function,4
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NRAS,Amplification,Inconclusive,Inconclusive,4
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CXCR4,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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PSMB2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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BRAF,Amplification,Oncogenic,Gain-of-function,4
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FLT1,Amplification,Inconclusive,Inconclusive,4
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DNMT3B,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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KDM5A,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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AR,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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MDM2,Amplification,Oncogenic,Gain-of-function,4
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YES1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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FOXA1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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MERTK,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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MAP2K1,Amplification,Inconclusive,Inconclusive,4
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MYCL,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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PPM1D,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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NKX2-1,Amplification,Oncogenic,Gain-of-function,4
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MYCN,Amplification,Oncogenic,Gain-of-function,4
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ERBB3,Amplification,Oncogenic,Gain-of-function,4
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ETV1,Amplification,Oncogenic,Gain-of-function,4
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SETD3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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ERBB2,Amplification,Oncogenic,Gain-of-function,4
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ROS1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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AURKA,Amplification,Oncogenic,Gain-of-function,4
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NTRK1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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ACKR3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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MDM4,Amplification,Oncogenic,Gain-of-function,4
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GATA3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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BCL6,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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JUN,Amplification,Oncogenic,Gain-of-function,4
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RNASEH2A,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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REV3L,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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PAK1,Amplification,Oncogenic,Gain-of-function,4
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CCND3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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FGF4,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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PIK3CB,Amplification,Likely Oncogenic,Gain-of-function,4
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GAB2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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KIT,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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RHOA,Amplification,Oncogenic,Gain-of-function,4
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RAF1,Amplification,Oncogenic,Gain-of-function,4
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CCND1,Amplification,Oncogenic,Gain-of-function,4
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ESR1,Amplification,Inconclusive,Inconclusive,4
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BAALC,Amplification,Likely Oncogenic,Likely Gain-of-function,3
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ID1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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KDR,Amplification,Oncogenic,Gain-of-function,4
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PIK3CA,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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MEF2B,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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JAK2,Amplification,Oncogenic,Gain-of-function,4
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FGF3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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MAPK1,Amplification,Likely Oncogenic,Gain-of-function,4
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CD274,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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MET,Amplification,Oncogenic,Gain-of-function,4
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FUS,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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FZR1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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YAP1,Amplification,Oncogenic,Gain-of-function,4
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CCNE1,Amplification,Oncogenic,Gain-of-function,4
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CRLF2,Amplification,Oncogenic,Gain-of-function,4
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NSD3,Amplification,Inconclusive,Inconclusive,4
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VEGFA,Amplification,Likely Oncogenic,Gain-of-function,4
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SMO,Amplification,Inconclusive,Inconclusive,4
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KRAS,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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ADHFE1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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IKBKE,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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RHEB,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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ALOX12B,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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BCL2L1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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BRD4,Amplification,Likely Oncogenic,Gain-of-function,4
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FGF19,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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TOP1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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KMT2A,Amplification,Inconclusive,Inconclusive,4
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RUNX1,Amplification,Oncogenic,Gain-of-function,4
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AGO2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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DDR2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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AKT1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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HMGA1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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TRIM27,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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CYP19A1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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IRS2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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PAX5,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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LGR5,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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CDK8,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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AKT2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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HMGA2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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CDK12,Amplification,Inconclusive,Inconclusive,4
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MITF,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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PDCD1LG2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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EZH2,Amplification,Oncogenic,Gain-of-function,4
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AKT3,Amplification,Oncogenic,Gain-of-function,4
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TERT,Amplification,Likely Oncogenic,Likely Gain-of-function,4
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KDM5C,Overexpression,Likely Oncogenic,Likely Gain-of-function,4
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AURKB,Overexpression,Likely Oncogenic,Likely Gain-of-function,4
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RHOA,Overexpression,Oncogenic,Gain-of-function,4
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CCNE1,Overexpression,Oncogenic,Gain-of-function,4
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EZH2,Overexpression,Oncogenic,Gain-of-function,4
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MSH2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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BBC3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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EP300,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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CHTF8,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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ATRIP,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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BAP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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TGFBR1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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MSH3,Deletion,Likely Oncogenic,Loss-of-function,4
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DAXX,Deletion,Oncogenic,Loss-of-function,4
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DUSP4,Deletion,Inconclusive,Inconclusive,4
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FANCA,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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ERRFI1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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BRIP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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PTPRD,Deletion,Oncogenic,Loss-of-function,4
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TGFBR2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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CTCF,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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NF1,Deletion,Likely Oncogenic,Loss-of-function,4
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FBXW7,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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RAD51B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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ATM,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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MLH1,Deletion,Likely Oncogenic,Loss-of-function,4
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BTG1,Deletion,Likely Oncogenic,Loss-of-function,4
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RELN,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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NOTCH1,Deletion,Likely Oncogenic,Likely Gain-of-function,4
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PIK3R1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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XRCC2,Deletion,Likely Neutral,Likely Loss-of-function,4
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ERCC4,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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NF2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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CIITA,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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SOX17,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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MSH6,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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HNF1A,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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BRCA2,Deletion,Oncogenic,Loss-of-function,4
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BCOR,Deletion,Oncogenic,Loss-of-function,4
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ATRX,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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DNMT3A,Deletion,Oncogenic,Loss-of-function,4
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CDKN2B,Deletion,Oncogenic,Loss-of-function,4
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PMS2,Deletion,Oncogenic,Loss-of-function,4
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PARP1,Deletion,Likely Oncogenic,Loss-of-function,4
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CDKN2C,Deletion,Oncogenic,Loss-of-function,4
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RAD17,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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CD58,Deletion,Likely Oncogenic,Loss-of-function,4
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EED,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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TP53BP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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BRCA1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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MED12,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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SMARCA4,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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CDKN2A,Deletion,Oncogenic,Loss-of-function,4
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DNMT3B,Deletion,Likely Oncogenic,Loss-of-function,4
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NPM1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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SOX9,Deletion,Oncogenic,Loss-of-function,4
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APC,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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BCL2L11,Deletion,Oncogenic,Likely Loss-of-function,4
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CIC,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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SHQ1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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RBM10,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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AXIN1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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FOXA1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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PBRM1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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EPHA3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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VHL,Deletion,Oncogenic,Likely Loss-of-function,4
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BCL10,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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KEAP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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CDC73,Deletion,Oncogenic,Loss-of-function,4
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COP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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CASP8,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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PTEN,Deletion,Oncogenic,Loss-of-function,4
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SETD2,Deletion,Oncogenic,Loss-of-function,4
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MGA,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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STK11,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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ALDH2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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TET2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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GATA3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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TP53,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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REV3L,Deletion,Inconclusive,Inconclusive,4
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SDHB,Deletion,Likely Oncogenic,Loss-of-function,4
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INPP4B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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LATS1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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TET1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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RNASEH2B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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PTPN11,Deletion,Oncogenic,Loss-of-function,4
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SMARCB1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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CREBBP,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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RAD21,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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LATS2,Deletion,Oncogenic,Loss-of-function,4
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ASXL2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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CDKN1A,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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KDM6A,Deletion,Oncogenic,Loss-of-function,4
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SDHD,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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ARID1A,Deletion,Likely Oncogenic,Loss-of-function,4
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FZR1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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ASXL1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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CDKN1B,Deletion,Oncogenic,Loss-of-function,4
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TNFAIP3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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ARID1B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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IKZF1,Deletion,Likely Oncogenic,Loss-of-function,4
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KMT2C,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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MAX,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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CBL,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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FH,Deletion,Likely Oncogenic,Loss-of-function,4
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RB1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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PPP2R2A,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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MTAP,Deletion,Likely Oncogenic,Likely Loss-of-function,4
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||
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SMAD4,Deletion,Likely Oncogenic,Loss-of-function,4
|
||
|
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CDH1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
|
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BARD1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
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TSC2,Deletion,Oncogenic,Likely Loss-of-function,4
|
||
|
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KMT2D,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
|
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HTATIP2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
|
|
RASA1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
|
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MEN1,Deletion,Oncogenic,Loss-of-function,4
|
||
|
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PAX5,Deletion,Likely Oncogenic,Loss-of-function,4
|
||
|
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BCL11B,Deletion,Likely Oncogenic,Loss-of-function,4
|
||
|
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B2M,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
|
|
SMAD3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
|
|
INTS6,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
|
|
CDK12,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
|
|
TSC1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
|
|
BIRC3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
|
|
RAD50,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
|
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FAT1,Deletion,Oncogenic,Loss-of-function,4
|
||
|
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SMAD2,Deletion,Likely Oncogenic,Loss-of-function,4
|
||
|
|
ANKRD11,Deletion,Likely Oncogenic,Loss-of-function,4
|
||
|
|
DICER1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
|
|
SETD3,Overexpression,Likely Oncogenic,Likely Gain-of-function,1
|
||
|
|
CRLF2,Overexpression,Oncogenic,Gain-of-function,10
|
||
|
|
FLT3,Amplification,Likely Oncogenic,Gain-of-function,2
|
||
|
|
PRDM1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
|
||
|
|
TLE1,Deletion,Likely Oncogenic,Likely Loss-of-function,2
|
||
|
|
TLE4,Deletion,Likely Oncogenic,Likely Loss-of-function,2
|