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筛选的条件: 1.去掉silent|intron|UTR|RNA 突变(#9) 2.是Somatic突变(#26) 3.EXAC_AF_EAS<0.01(#105) 4.坐标过滤(#5,6,7) 此验证的局限性在于panel之间的cds并非全包括关系,wes包含92% 650 cds, 650包含96% 160 cds。但数据的关联性较好,R2均大于98%。 g160 cds:0.308103 Mb g650 cds:1.357582 Mb 650plus50bp.bed cds:1.368272 Mb wes cds:31.180132 Mb