Gene,Alteration,Oncogenic,Mutation_Effect,Citations
CDK6,Amplification,Oncogenic,Gain-of-function,4
MCL1,Amplification,Oncogenic,Gain-of-function,4
PDGFRA,Amplification,Oncogenic,Gain-of-function,4
SRC,Amplification,Likely Oncogenic,Likely Gain-of-function,4
FGFR4,Amplification,Oncogenic,Gain-of-function,4
ECSIT,Amplification,Likely Oncogenic,Likely Gain-of-function,4
EGFR,Amplification,Oncogenic,Gain-of-function,4
HRAS,Amplification,Likely Oncogenic,Likely Gain-of-function,4
ERCC2,Amplification,Inconclusive,Inconclusive,4
ATP1A1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
UBR5,Amplification,Likely Oncogenic,Likely Gain-of-function,4
PDGFRB,Amplification,Inconclusive,Inconclusive,4
MYC,Amplification,Oncogenic,Gain-of-function,4
CDK4,Amplification,Oncogenic,Gain-of-function,4
RICTOR,Amplification,Oncogenic,Gain-of-function,4
ALK,Amplification,Likely Oncogenic,Likely Gain-of-function,4
FGFR2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
PHF19,Amplification,Likely Oncogenic,Likely Gain-of-function,4
RAC1,Amplification,Likely Oncogenic,Gain-of-function,4
CARD11,Amplification,Likely Oncogenic,Likely Gain-of-function,4
AXL,Amplification,Likely Oncogenic,Likely Gain-of-function,4
FGFR1,Amplification,Oncogenic,Gain-of-function,4
PIK3R2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
KAT7,Amplification,Likely Oncogenic,Likely Gain-of-function,4
GLI1,Amplification,Oncogenic,Gain-of-function,4
NRAS,Amplification,Inconclusive,Inconclusive,4
CXCR4,Amplification,Likely Oncogenic,Likely Gain-of-function,4
PSMB2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
BRAF,Amplification,Oncogenic,Gain-of-function,4
FLT1,Amplification,Inconclusive,Inconclusive,4
DNMT3B,Amplification,Likely Oncogenic,Likely Gain-of-function,4
KDM5A,Amplification,Likely Oncogenic,Likely Gain-of-function,4
AR,Amplification,Likely Oncogenic,Likely Gain-of-function,4
MDM2,Amplification,Oncogenic,Gain-of-function,4
YES1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
FOXA1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
MERTK,Amplification,Likely Oncogenic,Likely Gain-of-function,4
MAP2K1,Amplification,Inconclusive,Inconclusive,4
MYCL,Amplification,Likely Oncogenic,Likely Gain-of-function,4
PPM1D,Amplification,Likely Oncogenic,Likely Gain-of-function,4
NKX2-1,Amplification,Oncogenic,Gain-of-function,4
MYCN,Amplification,Oncogenic,Gain-of-function,4
ERBB3,Amplification,Oncogenic,Gain-of-function,4
ETV1,Amplification,Oncogenic,Gain-of-function,4
SETD3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
ERBB2,Amplification,Oncogenic,Gain-of-function,4
ROS1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
AURKA,Amplification,Oncogenic,Gain-of-function,4
NTRK1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
ACKR3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
MDM4,Amplification,Oncogenic,Gain-of-function,4
GATA3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
BCL6,Amplification,Likely Oncogenic,Likely Gain-of-function,4
JUN,Amplification,Oncogenic,Gain-of-function,4
RNASEH2A,Amplification,Likely Oncogenic,Likely Gain-of-function,4
REV3L,Amplification,Likely Oncogenic,Likely Gain-of-function,4
PAK1,Amplification,Oncogenic,Gain-of-function,4
CCND3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
FGF4,Amplification,Likely Oncogenic,Likely Gain-of-function,4
PIK3CB,Amplification,Likely Oncogenic,Gain-of-function,4
GAB2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
KIT,Amplification,Likely Oncogenic,Likely Gain-of-function,4
RHOA,Amplification,Oncogenic,Gain-of-function,4
RAF1,Amplification,Oncogenic,Gain-of-function,4
CCND1,Amplification,Oncogenic,Gain-of-function,4
ESR1,Amplification,Inconclusive,Inconclusive,4
BAALC,Amplification,Likely Oncogenic,Likely Gain-of-function,3
ID1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
KDR,Amplification,Oncogenic,Gain-of-function,4
PIK3CA,Amplification,Likely Oncogenic,Likely Gain-of-function,4
MEF2B,Amplification,Likely Oncogenic,Likely Gain-of-function,4
JAK2,Amplification,Oncogenic,Gain-of-function,4
FGF3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
MAPK1,Amplification,Likely Oncogenic,Gain-of-function,4
CD274,Amplification,Likely Oncogenic,Likely Gain-of-function,4
MET,Amplification,Oncogenic,Gain-of-function,4
FUS,Amplification,Likely Oncogenic,Likely Gain-of-function,4
FZR1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
YAP1,Amplification,Oncogenic,Gain-of-function,4
CCNE1,Amplification,Oncogenic,Gain-of-function,4
CRLF2,Amplification,Oncogenic,Gain-of-function,4
NSD3,Amplification,Inconclusive,Inconclusive,4
VEGFA,Amplification,Likely Oncogenic,Gain-of-function,4
SMO,Amplification,Inconclusive,Inconclusive,4
KRAS,Amplification,Likely Oncogenic,Likely Gain-of-function,4
ADHFE1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
IKBKE,Amplification,Likely Oncogenic,Likely Gain-of-function,4
RHEB,Amplification,Likely Oncogenic,Likely Gain-of-function,4
ALOX12B,Amplification,Likely Oncogenic,Likely Gain-of-function,4
BCL2L1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
BRD4,Amplification,Likely Oncogenic,Gain-of-function,4
FGF19,Amplification,Likely Oncogenic,Likely Gain-of-function,4
TOP1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
KMT2A,Amplification,Inconclusive,Inconclusive,4
RUNX1,Amplification,Oncogenic,Gain-of-function,4
AGO2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
DDR2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
AKT1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
HMGA1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
TRIM27,Amplification,Likely Oncogenic,Likely Gain-of-function,4
CYP19A1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
IRS2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
PAX5,Amplification,Likely Oncogenic,Likely Gain-of-function,4
LGR5,Amplification,Likely Oncogenic,Likely Gain-of-function,4
CDK8,Amplification,Likely Oncogenic,Likely Gain-of-function,4
AKT2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
HMGA2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
CDK12,Amplification,Inconclusive,Inconclusive,4
MITF,Amplification,Likely Oncogenic,Likely Gain-of-function,4
PDCD1LG2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
EZH2,Amplification,Oncogenic,Gain-of-function,4
AKT3,Amplification,Oncogenic,Gain-of-function,4
TERT,Amplification,Likely Oncogenic,Likely Gain-of-function,4
KDM5C,Overexpression,Likely Oncogenic,Likely Gain-of-function,4
AURKB,Overexpression,Likely Oncogenic,Likely Gain-of-function,4
RHOA,Overexpression,Oncogenic,Gain-of-function,4
CCNE1,Overexpression,Oncogenic,Gain-of-function,4
EZH2,Overexpression,Oncogenic,Gain-of-function,4
MSH2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
BBC3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
EP300,Deletion,Likely Oncogenic,Likely Loss-of-function,4
CHTF8,Deletion,Likely Oncogenic,Likely Loss-of-function,4
ATRIP,Deletion,Likely Oncogenic,Likely Loss-of-function,4
BAP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
TGFBR1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
MSH3,Deletion,Likely Oncogenic,Loss-of-function,4
DAXX,Deletion,Oncogenic,Loss-of-function,4
DUSP4,Deletion,Inconclusive,Inconclusive,4
FANCA,Deletion,Likely Oncogenic,Likely Loss-of-function,4
ERRFI1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
BRIP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
PTPRD,Deletion,Oncogenic,Loss-of-function,4
TGFBR2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
CTCF,Deletion,Likely Oncogenic,Likely Loss-of-function,4
NF1,Deletion,Likely Oncogenic,Loss-of-function,4
FBXW7,Deletion,Likely Oncogenic,Likely Loss-of-function,4
RAD51B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
ATM,Deletion,Likely Oncogenic,Likely Loss-of-function,4
MLH1,Deletion,Likely Oncogenic,Loss-of-function,4
BTG1,Deletion,Likely Oncogenic,Loss-of-function,4
RELN,Deletion,Likely Oncogenic,Likely Loss-of-function,4
NOTCH1,Deletion,Likely Oncogenic,Likely Gain-of-function,4
PIK3R1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
XRCC2,Deletion,Likely Neutral,Likely Loss-of-function,4
ERCC4,Deletion,Likely Oncogenic,Likely Loss-of-function,4
NF2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
CIITA,Deletion,Likely Oncogenic,Likely Loss-of-function,4
SOX17,Deletion,Likely Oncogenic,Likely Loss-of-function,4
MSH6,Deletion,Likely Oncogenic,Likely Loss-of-function,4
HNF1A,Deletion,Likely Oncogenic,Likely Loss-of-function,4
BRCA2,Deletion,Oncogenic,Loss-of-function,4
BCOR,Deletion,Oncogenic,Loss-of-function,4
ATRX,Deletion,Likely Oncogenic,Likely Loss-of-function,4
DNMT3A,Deletion,Oncogenic,Loss-of-function,4
CDKN2B,Deletion,Oncogenic,Loss-of-function,4
PMS2,Deletion,Oncogenic,Loss-of-function,4
PARP1,Deletion,Likely Oncogenic,Loss-of-function,4
CDKN2C,Deletion,Oncogenic,Loss-of-function,4
RAD17,Deletion,Likely Oncogenic,Likely Loss-of-function,4
CD58,Deletion,Likely Oncogenic,Loss-of-function,4
EED,Deletion,Likely Oncogenic,Likely Loss-of-function,4
TP53BP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
BRCA1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
MED12,Deletion,Likely Oncogenic,Likely Loss-of-function,4
SMARCA4,Deletion,Likely Oncogenic,Likely Loss-of-function,4
CDKN2A,Deletion,Oncogenic,Loss-of-function,4
DNMT3B,Deletion,Likely Oncogenic,Loss-of-function,4
NPM1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
SOX9,Deletion,Oncogenic,Loss-of-function,4
APC,Deletion,Likely Oncogenic,Likely Loss-of-function,4
BCL2L11,Deletion,Oncogenic,Likely Loss-of-function,4
CIC,Deletion,Likely Oncogenic,Likely Loss-of-function,4
SHQ1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
RBM10,Deletion,Likely Oncogenic,Likely Loss-of-function,4
AXIN1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
FOXA1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
PBRM1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
EPHA3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
VHL,Deletion,Oncogenic,Likely Loss-of-function,4
BCL10,Deletion,Likely Oncogenic,Likely Loss-of-function,4
KEAP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
CDC73,Deletion,Oncogenic,Loss-of-function,4
COP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
CASP8,Deletion,Likely Oncogenic,Likely Loss-of-function,4
PTEN,Deletion,Oncogenic,Loss-of-function,4
SETD2,Deletion,Oncogenic,Loss-of-function,4
MGA,Deletion,Likely Oncogenic,Likely Loss-of-function,4
STK11,Deletion,Likely Oncogenic,Likely Loss-of-function,4
ALDH2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
TET2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
GATA3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
TP53,Deletion,Likely Oncogenic,Likely Loss-of-function,4
REV3L,Deletion,Inconclusive,Inconclusive,4
SDHB,Deletion,Likely Oncogenic,Loss-of-function,4
INPP4B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
LATS1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
TET1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
RNASEH2B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
PTPN11,Deletion,Oncogenic,Loss-of-function,4
SMARCB1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
CREBBP,Deletion,Likely Oncogenic,Likely Loss-of-function,4
RAD21,Deletion,Likely Oncogenic,Likely Loss-of-function,4
LATS2,Deletion,Oncogenic,Loss-of-function,4
ASXL2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
CDKN1A,Deletion,Likely Oncogenic,Likely Loss-of-function,4
KDM6A,Deletion,Oncogenic,Loss-of-function,4
SDHD,Deletion,Likely Oncogenic,Likely Loss-of-function,4
ARID1A,Deletion,Likely Oncogenic,Loss-of-function,4
FZR1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
ASXL1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
CDKN1B,Deletion,Oncogenic,Loss-of-function,4
TNFAIP3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
ARID1B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
IKZF1,Deletion,Likely Oncogenic,Loss-of-function,4
KMT2C,Deletion,Likely Oncogenic,Likely Loss-of-function,4
MAX,Deletion,Likely Oncogenic,Likely Loss-of-function,4
CBL,Deletion,Likely Oncogenic,Likely Loss-of-function,4
FH,Deletion,Likely Oncogenic,Loss-of-function,4
RB1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
PPP2R2A,Deletion,Likely Oncogenic,Likely Loss-of-function,4
MTAP,Deletion,Likely Oncogenic,Likely Loss-of-function,4
SMAD4,Deletion,Likely Oncogenic,Loss-of-function,4
CDH1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
BARD1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
TSC2,Deletion,Oncogenic,Likely Loss-of-function,4
KMT2D,Deletion,Likely Oncogenic,Likely Loss-of-function,4
HTATIP2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
RASA1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
MEN1,Deletion,Oncogenic,Loss-of-function,4
PAX5,Deletion,Likely Oncogenic,Loss-of-function,4
BCL11B,Deletion,Likely Oncogenic,Loss-of-function,4
B2M,Deletion,Likely Oncogenic,Likely Loss-of-function,4
SMAD3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
INTS6,Deletion,Likely Oncogenic,Likely Loss-of-function,4
CDK12,Deletion,Likely Oncogenic,Likely Loss-of-function,4
TSC1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
BIRC3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
RAD50,Deletion,Likely Oncogenic,Likely Loss-of-function,4
FAT1,Deletion,Oncogenic,Loss-of-function,4
SMAD2,Deletion,Likely Oncogenic,Loss-of-function,4
ANKRD11,Deletion,Likely Oncogenic,Loss-of-function,4
DICER1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
SETD3,Overexpression,Likely Oncogenic,Likely Gain-of-function,1
CRLF2,Overexpression,Oncogenic,Gain-of-function,10
FLT3,Amplification,Likely Oncogenic,Gain-of-function,2
PRDM1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
TLE1,Deletion,Likely Oncogenic,Likely Loss-of-function,2
TLE4,Deletion,Likely Oncogenic,Likely Loss-of-function,2