From 6a22cb8463c6d1a36cf2e2059e8ae0363ad79cb7 Mon Sep 17 00:00:00 2001 From: chaopower Date: Mon, 29 Jan 2024 13:03:17 +0800 Subject: [PATCH] =?UTF-8?q?=E9=9C=80=E6=B1=82=E5=A4=84=E7=90=86?= MIME-Version: 1.0 Content-Type: text/plain; charset=UTF-8 Content-Transfer-Encoding: 8bit --- codes/chemo.py | 24 +++++++++++++++----- codes/filter_snpindel.pl | 47 ++++++++++++++++++++++++++++++++++------ codes/postprocess.py | 1 + database/info.csv | 12 +++++----- 4 files changed, 66 insertions(+), 18 deletions(-) diff --git a/codes/chemo.py b/codes/chemo.py index 8bb388b..4720dcf 100755 --- a/codes/chemo.py +++ b/codes/chemo.py @@ -104,26 +104,39 @@ class ChemoRun: alt = record.alts[0] # gt = '/'.join(list(map(str, sorted(record.samples.get(record.samples.keys()[0]).get('GT'))))) freq = record.samples.get(record.samples.keys()[-1]).get('AF')[0] + depth = record.samples.get(record.samples.keys()[-1]).get('DP') if freq > 0.9: gt = '1/1' elif 0.9 >= freq > 0.1: gt = '0/1' else: gt = '0/0' - fliter = pd.concat([fliter, drug_rsid_data[ + match_drug_rsid_data = drug_rsid_data[ (drug_rsid_data['chr'] == chrom) & (drug_rsid_data['end'] == end) & (drug_rsid_data['ref'] == ref) & (drug_rsid_data['alt'] == alt) & (drug_rsid_data['genotype'] == gt) - ]]) + ] + match_drug_rsid_data = match_drug_rsid_data.reset_index() + match_drug_rsid_data['chr'] = chrom + match_drug_rsid_data['pos'] = end + match_drug_rsid_data['freq'] = freq + match_drug_rsid_data['depth'] = depth + fliter = pd.concat([fliter, match_drug_rsid_data]) if fliter.empty: - fliter = pd.concat([fliter, drug_rsid_data[ + match_drug_rsid_data = drug_rsid_data[ (drug_rsid_data['chr'] == chrom) & (drug_rsid_data['end'] == end) & (drug_rsid_data['genotype'] == '0/0') - ]]) + ] + match_drug_rsid_data = match_drug_rsid_data.reset_index() + match_drug_rsid_data['chr'] = chrom + match_drug_rsid_data['pos'] = end + match_drug_rsid_data['freq'] = '.' + match_drug_rsid_data['depth'] = '.' + fliter = pd.concat([fliter, match_drug_rsid_data]) if fliter.empty: raise UserWarning( @@ -136,7 +149,8 @@ class ChemoRun: fliterdata.to_csv(respath, sep='\t', index=False) # 分类汇总 同位点，药物合并 drug.infos.txt - drugrsid = fliterdata[['drugname', 'genename', 'rsid', 'result', 'level', 'tips', 'drugsort']] + drugrsid = fliterdata[ + ['drugname', 'genename', 'rsid', 'result', 'level', 'tips', 'drugsort', 'chr', 'pos', 'freq', 'depth']] drugrsid = drugrsid.drop_duplicates() resdrugrsid = drugrsid.groupby(['drugname', 'genename', 'rsid', 'result', 'level', 'drugsort'])['tips'].agg( ','.join).reset_index() diff --git a/codes/filter_snpindel.pl b/codes/filter_snpindel.pl index 3b884da..2d0faa2 100755 --- a/codes/filter_snpindel.pl +++ b/codes/filter_snpindel.pl @@ -30,7 +30,8 @@ chomp($head); my @columns = split("\t", $head); my $new_head = join("\t", "Validated", "ClinicalSign", @columns[0 .. 6], - "Freq", @columns[7 .. 20, 23, 28, 32, 50, 56, 62, 101, 102], "Oncogenic", "Mutation_Effect", "genetag", "process"); + "Freq", @columns[7 .. 20, 23, 28, 32, 50, 56, 62, 101, 102], "Oncogenic", "Mutation_Effect", "is_oncogene", + "is_tumor_suppressor_gene", "genetag", "process"); if (!($pipeline eq 'somatic' || $pipeline eq 'tmb' || $pipeline eq 'hotspot' || $pipeline eq 'germline')) { die "useage: pipeline must be 'somatic' or 'germline' or 'hotspot or tmb'"; @@ -50,7 +51,9 @@ my @hhr2 = @$hhr2_ref; my @promoter = @$promoter_ref; my %transcript = transcript(); -my %oncogenic = get_oncogenic(); +my ($oncogenic, $is_oncogene) = get_oncogenic(); +my %oncogenic = %$oncogenic; +my %is_oncogene = %$is_oncogene; while () { chomp; @@ -144,7 +147,7 @@ while () { } elsif ($line[9] eq '.') { # splicing 位点 - if ($line[5] =~ /splicing/) { + if (($line[5] =~ /splicing/) or ($pipeline eq 'hotspot')) { my @hgvs = split(/;/, $line[7]); my $hgvs = $hgvs[0]; my $transcript_gene; @@ -166,6 +169,11 @@ while () { $hgvs =~ s/exon(\d+)/intron$intron;exon$exon/; $line[9] = join(":", ($gene, $hgvs)); } + # 不是前面2种情况，hotspot强制转换hgvs + elsif ($pipeline eq 'hotspot') { + print "$hgvs\n"; + $line[9] = join(":", ($gene, $hgvs)); + } else { push @reason, 'not_need_spl'; } @@ -177,6 +185,9 @@ while () { } else { + if ($line[8] eq 'intron') { + push @reason, 'not_need_spl_inron'; + } my @hgvs = split(/,/, $line[9]); my $hgvs = $hgvs[0]; my $transcript_gene; @@ -214,6 +225,13 @@ while () { if ((grep {$_ eq $gene} @promoter) and ($pipeline eq 'somatic') and ($gene eq 'TERT') and ($line[1] eq '1295228' and $line[4] eq 'A') or ($line[1] eq '1295250' and $line[4] eq 'A')) { @reason = (); + if ($line[1] eq '1295228') { + $line[9] = 'TERT:NM_198253:/:c.-124C>T (C228T)'; + } + else { + $line[9] = 'TERT:NM_198253:/:c.-146C>T (C250T)'; + } + $line[8] = 'promoter'; } if (@reason) { @@ -221,17 +239,27 @@ while () { next; } - my ($oncogenic_col, $mut_effect_col); + my ($oncogenic_col, $mut_effect_col, $is_oncogene_gene, $is_tumor_suppressor_gene); my $get_key = "$gene\_$protein"; if (exists $oncogenic{lc $get_key}) { my @get_values = split('&&', $oncogenic{lc $get_key}); $oncogenic_col = $get_values[0]; $mut_effect_col = $get_values[1]; + } else { $oncogenic_col = '.'; $mut_effect_col = '.'; } + if (exists $is_oncogene{lc $gene}) { + my @get_values = split('&&', $is_oncogene{lc $gene}); + $is_oncogene_gene = $get_values[0]; + $is_tumor_suppressor_gene = $get_values[1]; + } + else { + $is_oncogene_gene = '.'; + $is_tumor_suppressor_gene = '.'; + } my $clisig; if ($line[16] =~ /Likely_pathogenic|drug/i) { @@ -266,7 +294,9 @@ while () { $line[6] = $gene; my $genetag = join(";", @genetags); - my $new_line = join("\t", $validated, $clisig, @line[0 .. 6], $freq, @line[7 .. 20, 23, 28, 32, 50, 56, 62, 101, 102], $oncogenic_col, $mut_effect_col, $genetag, $pipeline); + my $new_line = join("\t", $validated, $clisig, + @line[0 .. 6], $freq, @line[7 .. 20, 23, 28, 32, 50, 56, 62, 101, 102], + $oncogenic_col, $mut_effect_col, $is_oncogene_gene, $is_tumor_suppressor_gene, $genetag, $pipeline); print OUT "$new_line\n"; print TAG_OUT "PASS\t", join("\t", @line), "\n"; @@ -339,13 +369,16 @@ sub transcript { # oncokb snv_indel 临床意义定义 sub get_oncogenic { my %sig; + my %sig_gene; open SNV_INDEL, "$database_path/snv_indel_mutation.csv"; ; while () { chomp; + $_ =~ s/\r//g; my @line = split(","); my $key = join("_", @line[0, 1]); - $sig{lc $key} = join("&&", @line[2, 3]); + $sig{lc $key} = join("&&", @line[2, 3, 7, 8]); + $sig_gene{lc $line[0]} = join("&&", @line[7, 8]); } - return %sig; + return (\%sig, \%sig_gene); } diff --git a/codes/postprocess.py b/codes/postprocess.py index cee66c1..ecac0a4 100755 --- a/codes/postprocess.py +++ b/codes/postprocess.py @@ -263,6 +263,7 @@ class PostProcess: filter_sum_df = filter_sum_df[cols] filter_sum_df = filter_sum_df.fillna('.') + filter_sum_df = filter_sum_df.sort_values(by='AMP_mut_level') filter_sum_res = filter_sum_df.to_dict('records') self.sheet['target_mut'] = filter_sum_res diff --git a/database/info.csv b/database/info.csv index 5e894b3..e1b845b 100755 --- a/database/info.csv +++ b/database/info.csv @@ -1,10 +1,10 @@ project_Id,project,project_Name,report_Name,CateCode,treatResult,probe,mutation,splicing,promoter,cnv,fusion,long_indel,chemotherapy_drug,HCS,MMR,HRR_I,HRR_II,Immune_predictor -LZ103,160gene,肿瘤160基因检测（组织版）,肿瘤个体化用药（160基因）检测,addTarget;addFusion;addCnv;addMsi;addMmr;addChemo;addHrr1;addHrr2;addHcs,NA,160,AKT1/ALK/APC/ATM/BARD1/BCL2L11/BRAF/BRCA1/BRCA2/BRIP1/CCND1/CCND2/CCND3/CDK12/CDK4/CDK6/CDKN2A/CHEK1/CHEK2/CSF1R/CTNNB1/DDR2/EGFR/ERBB2/ERBB3/ERBB4/FANCL/FBXW7/FGFR1/FGFR2/FGFR3/FLT3/GNA11/GNAQ/HRAS/IDH1/IDH2/JAK1/JAK2/JAK3/KDR/KIT/KRAS/MAP2K1/MET/MTOR/NF1/NRAS/NTRK1/NTRK2/NTRK3/PALB2/PDGFRA/PDGFRB/PIK3CA/PTEN/RAD51B/RAD51C/RAD51D/RAD54L/RB1/RET/ROS1/SMAD4/SMO/STK11/TERT/TP53/TSC1/TSC2/VHL/MDM2/MDM4/MSH2/MSH6/MLH1/PMS2/EPCAM/ATR/BAP1/BMPR1A/CDH1/FANCA/FANCM/MUTYH/NBN/ABCC2/ABCG2/ABRAXAS1/ACYP2/AR/ARID1A/ATIC/B2M/C8orf34/CBR3/CD274/CTNNA1/CYP1A1/CYP1B1/CYP2C19/CYP4B1/DHFR/DNMT3A/ERCC3/GATA3/GEN1/GREM1/HDAC2/MLH3/MRE11/MTR/MYC/NOTCH1/NT5C2/PDCD1LG2/PNPLA3/POLD1/POLE/PPM1D/RAD50/RRM1/SCG5/SDHA/SDHB/SDHC/SDHD/SEMA3C/SLC19A1/SLC28A3/SLCO1B1/SRC/STIM1/TAP1/TAP2/TOP1/TSPAN31/TUBB1/XRCC2,MET,TERT,CDK4/EGFR/ERBB2/FGFR1/FGFR2/FGFR3/FLT3/MET/MDM2/MDM4/CDKN2A,ALK/NTRK1/NTRK2/NTRK3/RET/ROS1,BCL2L11,ABCB1/CASP7/CDA/CYP19A1/CYP2C8/CYP2D6/CYP3A4/DPYD/DYNC2H1/ERCC1/ERCC2/GSTP1/HAS3/MTHFR/NQO1/SOD2/TPMT/TYMS/UGT1A1/XPC/XRCC1,ALK/APC/ATM/BRAF/BRCA1/BRCA2/CDH1/CDK4/CDKN2A/CHEK2/DNMT3A/EGFR/EPCAM/ERCC3/FANCA/HRAS/KRAS/MAP2K1/MET/MLH1/MSH2/MSH6/MUTYH/NBN/NF1/NRAS/PALB2/PMS2/POLD1/POLE/PTEN/RAD51D/RB1/RET/SDHA/SDHB/SDHC/SDHD/SMAD4/STK11/TP53/TSC1/TSC2/VHL,MSH2/MSH6/MLH1/PMS2/EPCAM,ATM/ATR/BARD1/BRCA1/BRCA2/BRIP1/CDK12/CHEK1/CHEK2/FANCA/FANCL/MLH1/NBN/PALB2/RAD51B/RAD51C/RAD51D/RAD54L,ARID1A/FANCM/HDAC2/POLD1/PTEN/RAD50,NA -LZ110,160gene,肿瘤160基因检测（血液版）,肿瘤个体化用药（160基因）检测,addTarget;addFusion;addCnv;addMsi;addMmr;addChemo;addHrr1;addHrr2;addHcs,NA,160,AKT1/ALK/APC/ATM/BARD1/BCL2L11/BRAF/BRCA1/BRCA2/BRIP1/CCND1/CCND2/CCND3/CDK12/CDK4/CDK6/CDKN2A/CHEK1/CHEK2/CSF1R/CTNNB1/DDR2/EGFR/ERBB2/ERBB3/ERBB4/FANCL/FBXW7/FGFR1/FGFR2/FGFR3/FLT3/GNA11/GNAQ/HRAS/IDH1/IDH2/JAK1/JAK2/JAK3/KDR/KIT/KRAS/MAP2K1/MET/MTOR/NF1/NRAS/NTRK1/NTRK2/NTRK3/PALB2/PDGFRA/PDGFRB/PIK3CA/PTEN/RAD51B/RAD51C/RAD51D/RAD54L/RB1/RET/ROS1/SMAD4/SMO/STK11/TERT/TP53/TSC1/TSC2/VHL/MDM2/MDM4/MSH2/MSH6/MLH1/PMS2/EPCAM/ATR/BAP1/BMPR1A/CDH1/FANCA/FANCM/MUTYH/NBN/ABCC2/ABCG2/ABRAXAS1/ACYP2/AR/ARID1A/ATIC/B2M/C8orf34/CBR3/CD274/CTNNA1/CYP1A1/CYP1B1/CYP2C19/CYP4B1/DHFR/DNMT3A/ERCC3/GATA3/GEN1/GREM1/HDAC2/MLH3/MRE11/MTR/MYC/NOTCH1/NT5C2/PDCD1LG2/PNPLA3/POLD1/POLE/PPM1D/RAD50/RRM1/SCG5/SDHA/SDHB/SDHC/SDHD/SEMA3C/SLC19A1/SLC28A3/SLCO1B1/SRC/STIM1/TAP1/TAP2/TOP1/TSPAN31/TUBB1/XRCC2,MET,TERT,CDK4/EGFR/ERBB2/FGFR1/FGFR2/FGFR3/FLT3/MET/MDM2/MDM4/CDKN2A,ALK/NTRK1/NTRK2/NTRK3/RET/ROS1,BCL2L11,ABCB1/CASP7/CDA/CYP19A1/CYP2C8/CYP2D6/CYP3A4/DPYD/DYNC2H1/ERCC1/ERCC2/GSTP1/HAS3/MTHFR/NQO1/SOD2/TPMT/TYMS/UGT1A1/XPC/XRCC1,ALK/APC/ATM/BRAF/BRCA1/BRCA2/CDH1/CDK4/CDKN2A/CHEK2/DNMT3A/EGFR/EPCAM/ERCC3/FANCA/HRAS/KRAS/MAP2K1/MET/MLH1/MSH2/MSH6/MUTYH/NBN/NF1/NRAS/PALB2/PMS2/POLD1/POLE/PTEN/RAD51D/RB1/RET/SDHA/SDHB/SDHC/SDHD/SMAD4/STK11/TP53/TSC1/TSC2/VHL,MSH2/MSH6/MLH1/PMS2/EPCAM,ATM/ATR/BARD1/BRCA1/BRCA2/BRIP1/CDK12/CHEK1/CHEK2/FANCA/FANCL/MLH1/NBN/PALB2/RAD51B/RAD51C/RAD51D/RAD54L,ARID1A/FANCM/HDAC2/POLD1/PTEN/RAD50,NA -LZ108,682gene,肿瘤682基因检测（组织版）,肿瘤精准诊疗基因检测（682基因）,addTarget;addFusion;addCnv;addMsi;addMmr;addChemo;addHrr1;addHrr2;addHcs;addbigPanel;addHpd;addNeoantigen;addTmb,NA,682,ABL1/AKT1/AKT2/AKT3/ALK/APC/ARAF/ATM/BARD1/BCL2L11/BRAF/BRCA1/BRCA2/BRIP1/BTK/CCND1/CCND2/CCND3/CDK12/CDK4/CDK6/CDKN2A/CDKN2B/CHEK1/CHEK2/CSF1R/CTNNB1/DDR2/EGFR/ERBB2/ERBB3/ERBB4/ESR1/EZH2/FANCL/FBXW7/FGFR1/FGFR2/FGFR3/FGFR4/FLT3/GNA11/GNAQ/HRAS/IDH1/IDH2/JAK1/JAK2/JAK3/KDR/KIT/KRAS/MAP2K1/MAP2K2/MET/MPL/MTOR/MYCN/MYD88/MDM2/MDM4/NF1/NF2/NRAS/NTRK1/NTRK2/NTRK3/PALB2/PDGFRA/PDGFRB/PIK3CA/PTCH1/PTEN/RAD51B/RAD51C/RAD51D/RAD54L/RAF1/RB1/RET/ROS1/SMAD4/SMARCB1/SMO/STK11/TERT/TP53/TSC1/TSC2/VHL/PPP2R2A/ARID1A/ATR/ATRX/BAP1/BLM/FANCA/FANCC/FANCD2/FANCE/FANCF/FANCG/FANCI/MDC1/MRE11/NBN/RAD50/RAD51/XRCC2/MSH2/MSH6/MLH1/PMS2/EPCAM/AXIN1/B2M/KEAP1/ERCC4/POLE/ARID1B/ARID2/EPHA3/EPHA5/EPHA7/POLD1/LRP1B/NOTCH1/NOTCH2/NOTCH3/BMPR1A/CDC73/CDH1/CEBPA/ERCC3/ERCC5/FH/FLCN/GATA2/HOXB13/MAX/MEN1/MITF/MSH3/MUTYH/PHOX2B/PMS1/PRKAR1A/PTPN11/RIT1/RNF43/SBDS/SDHA/SDHAF2/SDHB/SDHC/SDHD/SLX4/SOS1/SUFU/TMEM127/FANCB/ABCB9/ABCC2/ABCC4/ABCG2/ABRAXAS1/ACE2/ACVR1/ACVR1B/ACVR2A/ACYP2/ADGRA2/AGO2/ALOX12B/AMER1/ANKRD11/AR/ARFRP1/ARID5B/ASXL1/ASXL2/ATIC/AURKA/AURKB/AXIN2/AXL/BABAM1/BBC3/BCL10/BCL2/BCL2L1/BCL2L2/BCL6/BCOR/BCORL1/BCR/BIRC3/BIRC5/BLK/BRD4/BTG1/C8orf34/CALR/CANX/CARD11/CARM1/CASP8/CBFB/CBL/CBR3/CCN6/CCNE1/CCNQ/CD19/CD200/CD22/CD274/CD276/CD38/CD3D/CD3E/CD3G/CD40/CD52/CD74/CD79A/CD79B/CDC42/CDK2/CDK8/CDK9/CDKN1A/CDKN1B/CDKN2C/CENPA/CHD4/CHST3/CIC/COL5A1/COP1/CREBBP/CRKL/CRLF2/CSDE1/CSF3R/CSK/CSNK1A1/CTCF/CTLA4/CTNNA1/CTSB/CTSL/CTSS/CUL3/CUL4A/CXCR4/CYLD/CYP17A1/CYP1A1/CYP1B1/CYP2C19/CYP2E1/CYP4B1/CYSLTR2/DAXX/DCUN1D1/DDR1/DHFR/DICER1/DIS3/DMD/DNAJB1/DNMT1/DNMT3A/DNMT3B/DOT1L/DROSHA/DSCAM/DUSP4/E2F3/EED/EGF/EGFL7/EIF1AX/EIF4A2/EIF4E/ELF3/ELOC/EML4/EMSY/EP300/EPAS1/EPHA2/EPHB1/ERAP1/ERAP2/ERF/ERG/ERRFI1/ETV1/ETV4/ETV5/ETV6/EWSR1/EZH1/EZR/FANCM/FAS/FASTKD3/FAT1/FCGR3A/FGF1/FGF10/FGF12/FGF14/FGF19/FGF2/FGF23/FGF3/FGF4/FGF5/FGF6/FGF7/FGF8/FGF9/FGR/FLT1/FLT4/FOXA1/FOXL2/FOXO1/FOXP1/FRK/FRS2/FUBP1/FYN/GABRA6/GALNT14/GATA1/GATA3/GATA4/GATA6/GEN1/GID4/GLI1/GNA13/GNAS/GPS2/GREM1/GRIN2A/GRM3/GSK3B/H1-2/H2BC5/H3-3A/H3-3B/H3-4/H3-5/H3C1/H3C10/H3C11/H3C12/H3C13/H3C14/H3C2/H3C3/H3C4/H3C6/H3C7/H3C8/HAS3/HDAC2/HGF/HLA-A/HLA-B/HNF1A/HSD3B1/HSP90AA1/ICOSLG/ID3/IDE/IFI30/IFNGR1/IGF1/IGF1R/IGF2/IKBKE/IKZF1/IL10/IL2RA/IL2RB/IL2RG/IL6/IL7R/INHA/INHBA/INPP4A/INPP4B/INPPL1/INSR/IRF2/IRF4/IRS1/IRS2/ITK/JUN/KAT6A/KCNJ5/KDM5A/KDM5C/KDM6A/KEL/KLC3/KLF4/KLHL6/KMT2A/KMT2B/KMT2C/KMT2D/KMT5A/KNSTRN/LATS1/LATS2/LCK/LGMN/LIMK1/LMO1/LNPEP/LRIG3/LRP2/LTK/LYN/MALT1/MAP2K4/MAP2K7/MAP3K1/MAP3K13/MAP3K14/MAP4K5/MAPK1/MAPK3/MAPKAP1/MCL1/MED12/MEF2B/MERTK/MGA/MLH3/MSI1/MSI2/MST1/MST1R/MTR/MTRR/MYB/MYC/MYCL/MYOD1/NCOA3/NCOR1/NEGR1/NFE2L2/NFKBIA/NKX2-1/NKX3-1/NOS3/NOTCH4/NPEPPS/NPM1/NRDC/NRG1/NSD1/NSD2/NSD3/NT5C2/NTHL1/NUF2/NUP93/NUTM1/PAK1/PAK3/PAK5/PARP1/PARP2/PAX5/PBRM1/PCBP1/PCNA/PDCD1/PDCD1LG2/PDIA3/PDK1/PDPK1/PGR/PHF6/PIK3C2B/PIK3C2G/PIK3C3/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIM1/PLCG2/PLK2/PMAIP1/PNPLA3/PNRC1/POLB/POLR1G/PPARG/PPM1D/PPP2R1A/PPP4R2/PPP6C/PRDM1/PRDM14/PREX2/PRKCI/PRKD1/PRKDC/PRKN/PTGS2/PTK2/PTK6/PTP4A1/PTPRD/PTPRS/PTPRT/QKI/RAB35/RAC1/RAC2/RAD21/RAD52/RANBP2/RARA/RASA1/RBM10/RECQL/RECQL4/REL/RHEB/RHOA/RICTOR/RNU6-28P/ROCK1/RPL13/RPS6KA4/RPS6KB2/RPTOR/RRAGC/RRAS/RRAS2/RRM1/RSPO2/RTEL1/RUNX1/RXRA/RYBP/SCG5/SDC4/SEMA3C/SESN1/SESN2/SESN3/SETD2/SF3B1/SGK1/SH2B3/SH2D1A/SHOC2/SHQ1/SIK1/SLAMF7/SLC19A1/SLC22A2/SLC28A3/SLC34A2/SLCO1B1/SLCO1B3/SMAD2/SMAD3/SMARCA4/SMARCD1/SMYD3/SNCAIP/SOCS1/SOX10/SOX2/SOX17/SOX9/SPEN/SPOP/SPRED1/SPRY2/SRC/SRD5A2/SRMS/SRSF2/STAG2/STAT3/STAT4/STAT5A/STAT5B/STIM1/STK19/STK40/SUZ12/SYK/TAP1/TAP2/TAPBP/TAPBPL/TBX3/TCF3/TCF7L2/TEK/TENT5C/TET1/TET2/TGFBR1/TGFBR2/TIPARP/TMPRSS2/TNF/TNFAIP3/TNFRSF14/TNFRSF8/TNFSF11/TOP1/TP53BP1/TP63/TP73/TPP2/TRAF2/TRAF7/TSHR/TSPAN31/TUBB1/TYK2/TYRO3/U2AF1/UMPS/UPF1/VEGFA/VSIR/VTCN1/WAS/WT1/WWTR1/XIAP/XPO1/YAP1/YES1/ZFHX3/ZNF217/ZNF703,MET,TERT,CDK4/EGFR/ERBB2/FGFR1/FGFR2/FGFR3/FLT3/MET/MYCN/MDM2/MDM4/CDKN2A/CDKN2B,ALK/BRAF/FGFR1/FGFR2/FGFR3/NTRK1/NTRK2/NTRK3/RET/ROS1,BCL2L11,ABCB1/CDA/CYP19A1/CYP2B6/CYP2C8/CYP2D6/CYP3A4/DPYD/DYNC2H1/ERCC1/ERCC2/GSTP1/MTHFR/NQO1/NUDT15/SOD2/TPMT/TYMS/UGT1A1/XPC/XRCC1/CCND1,ALK/APC/ASXL1/ATM/ATRX/BAP1/BLM/BMPR1A/BRAF/BRCA1/BRCA2/BRIP1/CBL/CDC73/CDH1/CDK4/CDKN1B/CDKN2A/CEBPA/CHEK2/CREBBP/CTLA4/DICER1/DNMT3A/EGFR/EP300/EPCAM/ERCC4/ETV6/FANCA/FANCC/FANCD2/FANCE/FANCF/FANCG/FANCI/FANCL/FAS/FH/FLCN/GATA2/HOXB13/HRAS/IKZF1/KRAS/MAP2K1/MAP2K2/MAX/MEN1/MET/MITF/MLH1/MSH2/MSH3/MSH6/MUTYH/NBN/NF1/NF2/NKX2-1/NRAS/NTHL1/PALB2/PAX5/PHOX2B/PMS2/POLD1/POLE/PRKAR1A/PTCH1/PTEN/PTPN11/RAD51/RAD51C/RAD51D/RAF1/RB1/RET/RIT1/RNF43/RRAS2/RUNX1/SBDS/SDHA/SDHAF2/SDHB/SDHC/SDHD/SLX4/SMAD4/SMARCA4/SMARCB1/SOS1/STAT3/STK11/SUFU/TERT/TMEM127/TP53/TSC1/TSC2/VHL/WT1/XRCC2,MSH2/MSH6/MLH1/PMS2/EPCAM,ATM/ATR/BARD1/BRCA1/BRCA2/BRIP1/CDK12/CHEK1/CHEK2/FANCA/FANCL/MLH1/NBN/PALB2/RAD51B/RAD51C/RAD51D/RAD54L,ARID1A/FANCM/HDAC2/POLD1/PTEN/RAD50/PPP2R2A/ATR/ATRX/BAP1/BLM/FANCA/FANCC/FANCD2/FANCE/FANCF/FANCG/FANCI/MDC1/MRE11/NBN/RAD51/XRCC2/ARID1B/ARID2/EMSY/RAD52,MDM2/MDM4/EGFR/JAK1/JAK2/CTNNB1/AXIN1/APC/ALK/B2M/PTEN/STK11/KEAP1/ATM/ATR/BRCA1/BRCA2/CHEK1/CHEK2/BAP1/ERCC4/POLE/PALB2/RAD51C/RAD51D/ARID1A/ARID1B/ARID2/EPHA3/EPHA5/EPHA7/NF1/POLD1/LRP1B/NOTCH1/NOTCH2/NOTCH3 -LZ113,624gene,肿瘤624基因检测（血液版）,肿瘤精准诊疗基因检测（624基因）,addTarget;addFusion;addCnv;addMsi;addMmr;addChemo;addHrr1;addHrr2;addHcs;addbigPanel;addHpd;addNeoantigen;addTmb,NA,624,ABL1/AKT1/AKT2/AKT3/ALK/APC/ARAF/ATM/BARD1/BCL2L11/BRAF/BRCA1/BRCA2/BRIP1/BTK/CCND1/CCND2/CCND3/CCNE1/CDK12/CDK4/CDKN2A/CDKN2B/CHEK1/CHEK2/CSF1R/CSF3R/CTNNB1/CXCR4/DDR2/EGFR/ERBB2/ERBB3/ERBB4/ESR1/EZH2/FANCL/FBXW7/FGFR1/FGFR2/FGFR3/FGFR4/FLT3/GNA11/GNAQ/HRAS/IDH1/IDH2/JAK1/JAK2/JAK3/KDR/KIT/KRAS/MAP2K1/MAP2K2/MDM2/MET/MPL/MTOR/MYCN/MYD88/NF1/NF2/NRAS/NTRK1/NTRK2/NTRK3/PALB2/PDGFRA/PDGFRB/PIK3CA/PPP2R2A/PTCH1/PTEN/RAD51B/RAD51C/RAD51D/RAD54L/RAF1/RB1/RET/ROS1/SMAD4/SMARCB1/SMO/STK11/TP53/TSC1/TSC2/VHL/ARID1A/ARID1B/ARID2/ATR/ATRX/BAP1/BLM/EMSY/FANCA/FANCC/FANCD2/FANCE/FANCG/FANCM/HDAC2/MRE11/NBN/POLD1/RAD50/RAD51/RAD52/WRN/XRCC2/MLH1/MSH2/MSH6/PMS2/EPCAM/AXIN1/B2M/CD274/EPHA3/ERCC4/FGF19/FGF3/FGF4/KEAP1/MDM4/MTAP/NFE2L2/NOTCH1/NOTCH2/POLE/RNF43/SETD2/ASXL1/CBL/CDC73/CDH1/CDKN1B/CEBPA/CREBBP/DNMT3A/EP300/ERCC3/FAS/FH/FLCN/IKZF1/MAPK1/MEN1/MITF/NKX2-1/PAX5/PRKAR1A/PTPN11/SDHA/SDHB/SDHC/SDHD/SMARCA4/STAT3/SUFU/TERC/WT1/ABL2/ACSL6/ACVR1/ACVR1B/ACVR2A/AFDN/AFF1/AFF3/AKAP9/ALDH2/ALOX12B/AMER1/AR/ARFRP1/ARHGAP5/ARHGEF12/ASXL2/ATP1A1/ATP2B3/AURKA/AURKB/AXIN2/AXL/B3GALT2/BAX/BCL11A/BCL2/BCL2L1/BCL2L12/BCL2L2/BCL3/BCL6/BCL9/BCL9L/BCLAF1/BCOR/BCORL1/BCR/BIRC6/BMP5/BMPR1A/BRD3/BRD4/BTG1/BTG2/BUB1B/CALR/CAMTA1/CARD11/CASP8/CASP9/CBFB/CCDC6/CCR4/CD209/CD22/CD70/CD74/CD79A/CD79B/CDH10/CDH11/CDK8/CDKN1A/CDKN2C/CDX2/CEP43/CEP89/CHD2/CHD4/CIC/CIITA/CLIP1/CLTC/CLTCL1/CNBD1/CNTNAP2/CNTRL/COL1A1/COL2A1/CRKL/CRLF2/CRNKL1/CRTC1/CSMD3/CTCF/CTNNA1/CTNND1/CTNND2/CUL4A/CUX1/CYLD/CYP17A1/DAXX/DCBLD1/DCC/DDB2/DDR1/DDX10/DDX5/DDX6/DGCR8/DICER1/DIS3/DNM2/DNMT1/DOT1L/DROSHA/EBF1/EED/ELL/EML4/EPHA7/EPHB1/EPHB4/EPS15/ERCC5/ERG/ERRFI1/ETV1/ETV6/EVI2A/EVI2B/EXT2/EZR/FAM135B/FAM47C/FAT1/FAT3/FAT4/FBXO11/FCGR2B/FES/FGF10/FGF12/FGF14/FGF23/FGF6/FHIT/FKBP9/FLNA/FLT1/FLT4/FOXA1/FOXL2/FOXO3/FOXP1/FUBP1/GABRA6/GAS7/GATA1/GATA2/GATA3/GATA4/GATA6/GID4/GLI1/GNA13/GNAS/GRIN2A/GRM3/GSK3B/GSTTP2/H3-3A/H3C2/H4C9/HDAC1/HERPUD1/HGF/HIF1A/HIF1A-AS3/HIP1/HLA-A/HLA-B/HLA-C/HMGA1/HNF1A/HNRNPA2B1/HOXA11/HSP90AA1/HSP90AB1/ID3/IGF1R/IKBKE/IL6ST/IL7R/INPP4B/IRF2/IRF4/IRS2/IRS4/ISX/ITGAV/ITK/JUN/KAT6A/KAT6B/KAT7/KCNJ5/KDM5A/KDM5C/KDM6A/KEL/KIAA1549/KLF4/KLHL6/KMT2A/KMT2C/KMT2D/KNL1/KNSTRN/KTN1/LARP4B/LATS1/LATS2/LHFPL6/LMNA/LMO1/LMO2/LOC101928140/LOC645967/LPP/LRIG3/LRP1B/LRRC4/LSM14A/LTK/LYN/LZTR1/MACC1/MAF/MAP2K4/MAP3K13/MAX/MB21D2/MCL1/MECOM/MED12/MEF2B/MERTK/MKNK1/MLH3/MLLT3/MSI2/MSH3/MSN/MST1R/MUC1/MUC16/MUC4/MYB/MYC/MYCL/MYH11/MYOD1/N4BP2/NAB2/NACA/NBEA/NCOA2/NCOR1/NCOR2/NDRG1/NFATC2/NFKB2/NFKBIA/NFKBIE/NIN/NOTCH3/NPIPB2/NPM1/NRG1/NSD1/NSD2/NSD3/NUMA1/NUP214/NUTM2B/OLIG2/P2RY8/PABPC1/PARP1/PARP2/PARP3/PAX3/PBRM1/PCBP1/PCM1/PDCD1/PDCD1LG2/PDE4DIP/PDK1/PER1/PIK3C2B/PIK3C2G/PIK3CB/PIK3R1/PIM1/PLCG1/PMS1/POLQ/PPARG/PPFIBP1/PPM1D/PPP2R1A/PPP6C/PRCC/PRDM1/PRDM2/PREX2/PRKACA/PRKCB/PRKCI/PRKN/PTPN13/PTPN6/PTPRB/PTPRC/PTPRD/PTPRO/PTPRT/QKI/RABEP1/RAC1/RAD21/RANBP2/RARA/RBM10/RBM15/RECQL4/REL/RGPD3/RGS7/RHOA/RICTOR/RIT1/RNF213/ROBO2/RPL10/RPL22/RPL5/RPTOR/RUNX1/RUNX1T1/SALL4/SDC4/SEPTIN9/SETBP1/SETD1B/SETDB1/SF3B1/SGK1/SH2B3/SHTN1/SIRPA/SIX1/SIX2/SLC34A2/SMAD2/SMAD3/SMARCE1/SMC1A/SNCAIP/SNX29/SOCS1/SOX2/SOX9/SPECC1/SPEN/SPOP/SRC/SRSF2/SS18/SSX1/STAG1/STAG2/STAT5B/STAT6/STIL/SYK/TAL2/TAP1/TAP2/TBL1XR1/TBX3/TCEA1/TCF3/TCF7L2/TEC/TEK/TENT5C/TERT/TET1/TET2/TFE3/TFG/THRAP3/TIPARP/TMPRSS2/TNC/TNFAIP3/TNFRSF14/TNFRSF17/TP63/TPR/TRAF7/TRIM24/TRIM33/TRIP11/TRRAP/TSHR/TYRO3/U2AF1/UBR5/USP6/USP8/VEGFA/WAS/WNK2/XPO1/ZEB1/ZFHX3/ZMYM2/ZMYM3/ZNF217/ZNF479/ZNF703/ZNRF3/ZRSR2,MET,TERT,ALK/ATM/B2M/CCND1/CCND2/CCND3/CCNE1/CD274/CDK4/CDKN2A/CDKN2B/CSF1R/EGFR/ERBB2/FGFR1/FGFR2/FGFR3/FLT3/MDM2/MDM4/MET/MYCN/NF2/PTEN/RB1/SMARCB1,ALK/BRAF/FGFR1/FGFR2/FGFR3/MET/NTRK1/NTRK2/NTRK3/PDGFRA/RET/ROS1,BCL2L11,ABCB1/ABCG2/ACYP2/CASP7/CDA/CEP72/CYP19A1/CYP2B6/CYP2D6/CYP3A4/DHFR/DPYD/ERCC1/ERCC2/GSTP1/HAS3/MTHFR/MUTYH/NQO1/NUDT15/PNPLA3/RRM1/SLCO1B1/SLCO1B3/SOD2/TP53/TPMT/TYMS/UGT1A1/XRCC1,ALK/APC/ASXL1/ATM/ATRX/BAP1/BLM/BMPR1A/BRAF/BRCA1/BRCA2/BRIP1/CBL/CDC73/CDH1/CDK4/CDKN1B/CDKN2A/CEBPA/CHEK2/CREBBP/DICER1/DNMT3A/EGFR/EP300/EPCAM/ERCC3/ERCC4/ETV6/FANCA/FANCC/FANCD2/FANCE/FANCG/FANCL/FANCM/FAS/FH/FLCN/GATA2/HRAS/IKZF1/KRAS/LZTR1/MAP2K1/MAP2K2/MAPK1/MEN1/MET/MITF/MLH1/MSH2/MSH3/MSH6/MUTYH/NBN/NF1/NF2/NKX2-1/NRAS/PALB2/PAX5/PMS2/POLD1/POLE/PRKAR1A/PTCH1/PTEN/PTPN11/RAD51/RAD51C/RAD51D/RAF1/RB1/RET/RNF43/RUNX1/SDHA/SDHB/SDHC/SDHD/SMAD4/SMARCA4/SMARCB1/STAT3/STK11/SUFU/TERC/TP53/TSC1/TSC2/VHL/WRN/WT1/XRCC2,MSH2/MSH6/MLH1/PMS2/EPCAM,ATM/ATR/BARD1/BRCA1/BRCA2/BRIP1/CDK12/CHEK1/CHEK2/FANCA/FANCL/MLH1/NBN/PALB2/RAD51B/RAD51C/RAD51D/RAD54L,ARID1A/FANCM/HDAC2/POLD1/PTEN/RAD50/PPP2R2A/ATR/ATRX/BAP1/BLM/FANCA/FANCC/FANCD2/FANCE/FANCG/MRE11/NBN/RAD51/XRCC2/ARID1B/ARID2/EMSY/RAD52/WRN,CCND1/ALK/APC/ARID1A/ATM/ATR/AXIN1/B2M/BAP1/BRCA1/BRCA2/BRIP1/CD274/CDK12/CDKN2A/CDKN2B/CHEK1/CHEK2/CTNNB1/EGFR/EPHA3/ERCC4/FGF19/FGF3/FGF4/JAK1/JAK2/KEAP1/MDM2/MDM4/MRE11/MTAP/NBN/NF1/NFE2L2/NOTCH1/NOTCH2/NTRK3/PALB2/POLD1/POLE/PTEN/RAD50/RAD51C/RAD51D/RNF43/SETD2/SMO/STK11 -LZ102,lung_17_gene,肺癌17基因检测（组织版）,肺癌17基因检测报告（组织版）,addTarget;addFusion;addCnv,ST21,17,ALK/AKT1/BRAF/EGFR/ERBB2/KRAS/MAP2K1/MET/PIK3CA/PTEN/NTRK1/NTRK2/NTRK3/NRAS/RET/ROS1/BCL2L11,MET,NA,EGFR/ERBB2/MET,ALK/NTRK1/NTRK2/NTRK3/RET/ROS1,BCL2L11,NA,NA,NA,NA,NA,NA -LZ111,lung_17_gene,肺癌17基因检测（血液版）,肺癌17基因检测报告（血液版）,addTarget;addFusion;addCnv,ST21,17,ALK/AKT1/BRAF/EGFR/ERBB2/KRAS/MAP2K1/MET/PIK3CA/PTEN/NTRK1/NTRK2/NTRK3/NRAS/RET/ROS1/BCL2L11,MET,NA,EGFR/ERBB2/MET,ALK/NTRK1/NTRK2/NTRK3/RET/ROS1,BCL2L11,NA,NA,NA,NA,NA,NA +LZ103,160gene,肿瘤160基因检测（组织版）,肿瘤个体化用药（160基因）检测,addTarget;addFusion;addCnv;addMsi;addMmr;addChemo;addHrr1;addHrr2;addHcs;addbigPanel,NA,160,AKT1/ALK/APC/ATM/BARD1/BCL2L11/BRAF/BRCA1/BRCA2/BRIP1/CCND1/CCND2/CCND3/CDK12/CDK4/CDK6/CDKN2A/CHEK1/CHEK2/CSF1R/CTNNB1/DDR2/EGFR/ERBB2/ERBB3/ERBB4/FANCL/FBXW7/FGFR1/FGFR2/FGFR3/FLT3/GNA11/GNAQ/HRAS/IDH1/IDH2/JAK1/JAK2/JAK3/KDR/KIT/KRAS/MAP2K1/MET/MTOR/NF1/NRAS/NTRK1/NTRK2/NTRK3/PALB2/PDGFRA/PDGFRB/PIK3CA/PTEN/RAD51B/RAD51C/RAD51D/RAD54L/RB1/RET/ROS1/SMAD4/SMO/STK11/TERT/TP53/TSC1/TSC2/VHL/MDM2/MDM4/MSH2/MSH6/MLH1/PMS2/EPCAM/ATR/BAP1/BMPR1A/CDH1/FANCA/FANCM/MUTYH/NBN/ABCC2/ABCG2/ABRAXAS1/ACYP2/AR/ARID1A/ATIC/B2M/C8orf34/CBR3/CD274/CTNNA1/CYP1A1/CYP1B1/CYP2C19/CYP4B1/DHFR/DNMT3A/ERCC3/GATA3/GEN1/GREM1/HDAC2/MLH3/MRE11/MTR/MYC/NOTCH1/NT5C2/PDCD1LG2/PNPLA3/POLD1/POLE/PPM1D/RAD50/RRM1/SCG5/SDHA/SDHB/SDHC/SDHD/SEMA3C/SLC19A1/SLC28A3/SLCO1B1/SRC/STIM1/TAP1/TAP2/TOP1/TSPAN31/TUBB1/XRCC2,MET,TERT,CDK4/EGFR/ERBB2/FGFR1/FGFR2/FGFR3/FLT3/MET/MDM2/MDM4/CDKN2A,ALK/NTRK1/NTRK2/NTRK3/RET/ROS1,BCL2L11,ABCB1/CASP7/CDA/CYP19A1/CYP2C8/CYP2D6/CYP3A4/DPYD/DYNC2H1/ERCC1/ERCC2/GSTP1/HAS3/MTHFR/NQO1/SOD2/TPMT/TYMS/UGT1A1/XPC/XRCC1,ALK/APC/ATM/BRAF/BRCA1/BRCA2/CDH1/CDK4/CDKN2A/CHEK2/DNMT3A/EGFR/EPCAM/ERCC3/FANCA/HRAS/KRAS/MAP2K1/MET/MLH1/MSH2/MSH6/MUTYH/NBN/NF1/NRAS/PALB2/PMS2/POLD1/POLE/PTEN/RAD51D/RB1/RET/SDHA/SDHB/SDHC/SDHD/SMAD4/STK11/TP53/TSC1/TSC2/VHL,MSH2/MSH6/MLH1/PMS2/EPCAM,ATM/ATR/BARD1/BRCA1/BRCA2/BRIP1/CDK12/CHEK1/CHEK2/FANCA/FANCL/MLH1/NBN/PALB2/RAD51B/RAD51C/RAD51D/RAD54L,ARID1A/FANCM/HDAC2/POLD1/PTEN/RAD50,NA +LZ110,160gene,肿瘤160基因检测（血液版）,肿瘤个体化用药（160基因）检测,addTarget;addFusion;addCnv;addMsi;addMmr;addChemo;addHrr1;addHrr2;addHcs;addbigPanel,NA,160,AKT1/ALK/APC/ATM/BARD1/BCL2L11/BRAF/BRCA1/BRCA2/BRIP1/CCND1/CCND2/CCND3/CDK12/CDK4/CDK6/CDKN2A/CHEK1/CHEK2/CSF1R/CTNNB1/DDR2/EGFR/ERBB2/ERBB3/ERBB4/FANCL/FBXW7/FGFR1/FGFR2/FGFR3/FLT3/GNA11/GNAQ/HRAS/IDH1/IDH2/JAK1/JAK2/JAK3/KDR/KIT/KRAS/MAP2K1/MET/MTOR/NF1/NRAS/NTRK1/NTRK2/NTRK3/PALB2/PDGFRA/PDGFRB/PIK3CA/PTEN/RAD51B/RAD51C/RAD51D/RAD54L/RB1/RET/ROS1/SMAD4/SMO/STK11/TERT/TP53/TSC1/TSC2/VHL/MDM2/MDM4/MSH2/MSH6/MLH1/PMS2/EPCAM/ATR/BAP1/BMPR1A/CDH1/FANCA/FANCM/MUTYH/NBN/ABCC2/ABCG2/ABRAXAS1/ACYP2/AR/ARID1A/ATIC/B2M/C8orf34/CBR3/CD274/CTNNA1/CYP1A1/CYP1B1/CYP2C19/CYP4B1/DHFR/DNMT3A/ERCC3/GATA3/GEN1/GREM1/HDAC2/MLH3/MRE11/MTR/MYC/NOTCH1/NT5C2/PDCD1LG2/PNPLA3/POLD1/POLE/PPM1D/RAD50/RRM1/SCG5/SDHA/SDHB/SDHC/SDHD/SEMA3C/SLC19A1/SLC28A3/SLCO1B1/SRC/STIM1/TAP1/TAP2/TOP1/TSPAN31/TUBB1/XRCC2,MET,TERT,CDK4/EGFR/ERBB2/FGFR1/FGFR2/FGFR3/FLT3/MET/MDM2/MDM4/CDKN2A,ALK/NTRK1/NTRK2/NTRK3/RET/ROS1,BCL2L11,ABCB1/CASP7/CDA/CYP19A1/CYP2C8/CYP2D6/CYP3A4/DPYD/DYNC2H1/ERCC1/ERCC2/GSTP1/HAS3/MTHFR/NQO1/SOD2/TPMT/TYMS/UGT1A1/XPC/XRCC1,ALK/APC/ATM/BRAF/BRCA1/BRCA2/CDH1/CDK4/CDKN2A/CHEK2/DNMT3A/EGFR/EPCAM/ERCC3/FANCA/HRAS/KRAS/MAP2K1/MET/MLH1/MSH2/MSH6/MUTYH/NBN/NF1/NRAS/PALB2/PMS2/POLD1/POLE/PTEN/RAD51D/RB1/RET/SDHA/SDHB/SDHC/SDHD/SMAD4/STK11/TP53/TSC1/TSC2/VHL,MSH2/MSH6/MLH1/PMS2/EPCAM,ATM/ATR/BARD1/BRCA1/BRCA2/BRIP1/CDK12/CHEK1/CHEK2/FANCA/FANCL/MLH1/NBN/PALB2/RAD51B/RAD51C/RAD51D/RAD54L,ARID1A/FANCM/HDAC2/POLD1/PTEN/RAD50,NA +LZ108,682gene,肿瘤682基因检测（组织版）,肿瘤精准诊疗基因检测（682基因）,addTarget;addFusion;addCnv;addMsi;addMmr;addChemo;addHrr1;addHrr2;addHcs;addbigPanel;addHpd;addNeoantigen;addTmb,NA,682,ABL1/AKT1/AKT2/AKT3/ALK/APC/ARAF/ATM/BARD1/BCL2L11/BRAF/BRCA1/BRCA2/BRIP1/BTK/CCND1/CCND2/CCND3/CDK12/CDK4/CDK6/CDKN2A/CDKN2B/CHEK1/CHEK2/CSF1R/CTNNB1/DDR2/EGFR/ERBB2/ERBB3/ERBB4/ESR1/EZH2/FANCL/FBXW7/FGFR1/FGFR2/FGFR3/FGFR4/FLT3/GNA11/GNAQ/HRAS/IDH1/IDH2/JAK1/JAK2/JAK3/KDR/KIT/KRAS/MAP2K1/MAP2K2/MET/MPL/MTOR/MYCN/MYD88/MDM2/MDM4/NF1/NF2/NRAS/NTRK1/NTRK2/NTRK3/PALB2/PDGFRA/PDGFRB/PIK3CA/PTCH1/PTEN/RAD51B/RAD51C/RAD51D/RAD54L/RAF1/RB1/RET/ROS1/SMAD4/SMARCB1/SMO/STK11/TERT/TP53/TSC1/TSC2/VHL/PPP2R2A/ARID1A/ATR/ATRX/BAP1/BLM/FANCA/FANCC/FANCD2/FANCE/FANCF/FANCG/FANCI/MDC1/MRE11/NBN/RAD50/RAD51/XRCC2/MSH2/MSH6/MLH1/PMS2/EPCAM/AXIN1/B2M/KEAP1/ERCC4/POLE/ARID1B/ARID2/EPHA3/EPHA5/EPHA7/POLD1/LRP1B/NOTCH1/NOTCH2/NOTCH3/BMPR1A/CDC73/CDH1/CEBPA/ERCC3/ERCC5/FH/FLCN/GATA2/HOXB13/MAX/MEN1/MITF/MSH3/MUTYH/PHOX2B/PMS1/PRKAR1A/PTPN11/RIT1/RNF43/SBDS/SDHA/SDHAF2/SDHB/SDHC/SDHD/SLX4/SOS1/SUFU/TMEM127/FANCB/ABCB9/ABCC2/ABCC4/ABCG2/ABRAXAS1/ACE2/ACVR1/ACVR1B/ACVR2A/ACYP2/ADGRA2/AGO2/ALOX12B/AMER1/ANKRD11/AR/ARFRP1/ARID5B/ASXL1/ASXL2/ATIC/AURKA/AURKB/AXIN2/AXL/BABAM1/BBC3/BCL10/BCL2/BCL2L1/BCL2L2/BCL6/BCOR/BCORL1/BCR/BIRC3/BIRC5/BLK/BRD4/BTG1/C8orf34/CALR/CANX/CARD11/CARM1/CASP8/CBFB/CBL/CBR3/CCN6/CCNE1/CCNQ/CD19/CD200/CD22/CD274/CD276/CD38/CD3D/CD3E/CD3G/CD40/CD52/CD74/CD79A/CD79B/CDC42/CDK2/CDK8/CDK9/CDKN1A/CDKN1B/CDKN2C/CENPA/CHD4/CHST3/CIC/COL5A1/COP1/CREBBP/CRKL/CRLF2/CSDE1/CSF3R/CSK/CSNK1A1/CTCF/CTLA4/CTNNA1/CTSB/CTSL/CTSS/CUL3/CUL4A/CXCR4/CYLD/CYP17A1/CYP1A1/CYP1B1/CYP2C19/CYP2E1/CYP4B1/CYSLTR2/DAXX/DCUN1D1/DDR1/DHFR/DICER1/DIS3/DMD/DNAJB1/DNMT1/DNMT3A/DNMT3B/DOT1L/DROSHA/DSCAM/DUSP4/E2F3/EED/EGF/EGFL7/EIF1AX/EIF4A2/EIF4E/ELF3/ELOC/EML4/EMSY/EP300/EPAS1/EPHA2/EPHB1/ERAP1/ERAP2/ERF/ERG/ERRFI1/ETV1/ETV4/ETV5/ETV6/EWSR1/EZH1/EZR/FANCM/FAS/FASTKD3/FAT1/FCGR3A/FGF1/FGF10/FGF12/FGF14/FGF19/FGF2/FGF23/FGF3/FGF4/FGF5/FGF6/FGF7/FGF8/FGF9/FGR/FLT1/FLT4/FOXA1/FOXL2/FOXO1/FOXP1/FRK/FRS2/FUBP1/FYN/GABRA6/GALNT14/GATA1/GATA3/GATA4/GATA6/GEN1/GID4/GLI1/GNA13/GNAS/GPS2/GREM1/GRIN2A/GRM3/GSK3B/H1-2/H2BC5/H3-3A/H3-3B/H3-4/H3-5/H3C1/H3C10/H3C11/H3C12/H3C13/H3C14/H3C2/H3C3/H3C4/H3C6/H3C7/H3C8/HAS3/HDAC2/HGF/HLA-A/HLA-B/HNF1A/HSD3B1/HSP90AA1/ICOSLG/ID3/IDE/IFI30/IFNGR1/IGF1/IGF1R/IGF2/IKBKE/IKZF1/IL10/IL2RA/IL2RB/IL2RG/IL6/IL7R/INHA/INHBA/INPP4A/INPP4B/INPPL1/INSR/IRF2/IRF4/IRS1/IRS2/ITK/JUN/KAT6A/KCNJ5/KDM5A/KDM5C/KDM6A/KEL/KLC3/KLF4/KLHL6/KMT2A/KMT2B/KMT2C/KMT2D/KMT5A/KNSTRN/LATS1/LATS2/LCK/LGMN/LIMK1/LMO1/LNPEP/LRIG3/LRP2/LTK/LYN/MALT1/MAP2K4/MAP2K7/MAP3K1/MAP3K13/MAP3K14/MAP4K5/MAPK1/MAPK3/MAPKAP1/MCL1/MED12/MEF2B/MERTK/MGA/MLH3/MSI1/MSI2/MST1/MST1R/MTR/MTRR/MYB/MYC/MYCL/MYOD1/NCOA3/NCOR1/NEGR1/NFE2L2/NFKBIA/NKX2-1/NKX3-1/NOS3/NOTCH4/NPEPPS/NPM1/NRDC/NRG1/NSD1/NSD2/NSD3/NT5C2/NTHL1/NUF2/NUP93/NUTM1/PAK1/PAK3/PAK5/PARP1/PARP2/PAX5/PBRM1/PCBP1/PCNA/PDCD1/PDCD1LG2/PDIA3/PDK1/PDPK1/PGR/PHF6/PIK3C2B/PIK3C2G/PIK3C3/PIK3CB/PIK3CD/PIK3CG/PIK3R1/PIK3R2/PIK3R3/PIM1/PLCG2/PLK2/PMAIP1/PNPLA3/PNRC1/POLB/POLR1G/PPARG/PPM1D/PPP2R1A/PPP4R2/PPP6C/PRDM1/PRDM14/PREX2/PRKCI/PRKD1/PRKDC/PRKN/PTGS2/PTK2/PTK6/PTP4A1/PTPRD/PTPRS/PTPRT/QKI/RAB35/RAC1/RAC2/RAD21/RAD52/RANBP2/RARA/RASA1/RBM10/RECQL/RECQL4/REL/RHEB/RHOA/RICTOR/RNU6-28P/ROCK1/RPL13/RPS6KA4/RPS6KB2/RPTOR/RRAGC/RRAS/RRAS2/RRM1/RSPO2/RTEL1/RUNX1/RXRA/RYBP/SCG5/SDC4/SEMA3C/SESN1/SESN2/SESN3/SETD2/SF3B1/SGK1/SH2B3/SH2D1A/SHOC2/SHQ1/SIK1/SLAMF7/SLC19A1/SLC22A2/SLC28A3/SLC34A2/SLCO1B1/SLCO1B3/SMAD2/SMAD3/SMARCA4/SMARCD1/SMYD3/SNCAIP/SOCS1/SOX10/SOX2/SOX17/SOX9/SPEN/SPOP/SPRED1/SPRY2/SRC/SRD5A2/SRMS/SRSF2/STAG2/STAT3/STAT4/STAT5A/STAT5B/STIM1/STK19/STK40/SUZ12/SYK/TAP1/TAP2/TAPBP/TAPBPL/TBX3/TCF3/TCF7L2/TEK/TENT5C/TET1/TET2/TGFBR1/TGFBR2/TIPARP/TMPRSS2/TNF/TNFAIP3/TNFRSF14/TNFRSF8/TNFSF11/TOP1/TP53BP1/TP63/TP73/TPP2/TRAF2/TRAF7/TSHR/TSPAN31/TUBB1/TYK2/TYRO3/U2AF1/UMPS/UPF1/VEGFA/VSIR/VTCN1/WAS/WT1/WWTR1/XIAP/XPO1/YAP1/YES1/ZFHX3/ZNF217/ZNF703/HDAC1,MET,TERT,CDK4/EGFR/ERBB2/FGFR1/FGFR2/FGFR3/FLT3/MET/MYCN/MDM2/MDM4/CDKN2A/CDKN2B,ALK/BRAF/FGFR1/FGFR2/FGFR3/NTRK1/NTRK2/NTRK3/RET/ROS1,BCL2L11,ABCB1/CDA/CYP19A1/CYP2B6/CYP2C8/CYP2D6/CYP3A4/DPYD/DYNC2H1/ERCC1/ERCC2/GSTP1/MTHFR/NQO1/NUDT15/SOD2/TPMT/TYMS/UGT1A1/XPC/XRCC1/CCND1,ALK/APC/ASXL1/ATM/ATRX/BAP1/BLM/BMPR1A/BRAF/BRCA1/BRCA2/BRIP1/CBL/CDC73/CDH1/CDK4/CDKN1B/CDKN2A/CEBPA/CHEK2/CREBBP/CTLA4/DICER1/DNMT3A/EGFR/EP300/EPCAM/ERCC4/ETV6/FANCA/FANCC/FANCD2/FANCE/FANCF/FANCG/FANCI/FANCL/FAS/FH/FLCN/GATA2/HOXB13/HRAS/IKZF1/KRAS/MAP2K1/MAP2K2/MAX/MEN1/MET/MITF/MLH1/MSH2/MSH3/MSH6/MUTYH/NBN/NF1/NF2/NKX2-1/NRAS/NTHL1/PALB2/PAX5/PHOX2B/PMS2/POLD1/POLE/PRKAR1A/PTCH1/PTEN/PTPN11/RAD51/RAD51C/RAD51D/RAF1/RB1/RET/RIT1/RNF43/RRAS2/RUNX1/SBDS/SDHA/SDHAF2/SDHB/SDHC/SDHD/SLX4/SMAD4/SMARCA4/SMARCB1/SOS1/STAT3/STK11/SUFU/TERT/TMEM127/TP53/TSC1/TSC2/VHL/WT1/XRCC2,MSH2/MSH6/MLH1/PMS2/EPCAM,ATM/ATR/BARD1/BRCA1/BRCA2/BRIP1/CDK12/CHEK1/CHEK2/FANCA/FANCL/MLH1/NBN/PALB2/RAD51B/RAD51C/RAD51D/RAD54L,ARID1A/FANCM/HDAC2/POLD1/PTEN/RAD50/PPP2R2A/ATR/ATRX/BAP1/BLM/FANCA/FANCC/FANCD2/FANCE/FANCF/FANCG/FANCI/MDC1/MRE11/NBN/RAD51/XRCC2/ARID1B/ARID2/EMSY/RAD52,MDM2/MDM4/EGFR/JAK1/JAK2/CTNNB1/AXIN1/APC/ALK/B2M/PTEN/STK11/KEAP1/ATM/ATR/BRCA1/BRCA2/CHEK1/CHEK2/BAP1/ERCC4/POLE/PALB2/RAD51C/RAD51D/ARID1A/ARID1B/ARID2/EPHA3/EPHA5/EPHA7/NF1/POLD1/LRP1B/NOTCH1/NOTCH2/NOTCH3 +LZ113,624gene,肿瘤624基因检测（血液版）,肿瘤精准诊疗基因检测（624基因）,addTarget;addFusion;addCnv;addMsi;addMmr;addChemo;addHrr1;addHrr2;addHcs;addbigPanel;addHpd;addNeoantigen;addTmb,NA,624,ABL1/AKT1/AKT2/AKT3/ALK/APC/ARAF/ATM/BARD1/BCL2L11/BRAF/BRCA1/BRCA2/BRIP1/BTK/CCND1/CCND2/CCND3/CCNE1/CDK12/CDK4/CDKN2A/CDKN2B/CHEK1/CHEK2/CSF1R/CSF3R/CTNNB1/CXCR4/DDR2/EGFR/ERBB2/ERBB3/ERBB4/ESR1/EZH2/FANCL/FBXW7/FGFR1/FGFR2/FGFR3/FGFR4/FLT3/GNA11/GNAQ/HRAS/IDH1/IDH2/JAK1/JAK2/JAK3/KDR/KIT/KRAS/MAP2K1/MAP2K2/MDM2/MET/MPL/MTOR/MYCN/MYD88/NF1/NF2/NRAS/NTRK1/NTRK2/NTRK3/PALB2/PDGFRA/PDGFRB/PIK3CA/PPP2R2A/PTCH1/PTEN/RAD51B/RAD51C/RAD51D/RAD54L/RAF1/RB1/RET/ROS1/SMAD4/SMARCB1/SMO/STK11/TP53/TSC1/TSC2/VHL/ARID1A/ARID1B/ARID2/ATR/ATRX/BAP1/BLM/EMSY/FANCA/FANCC/FANCD2/FANCE/FANCG/FANCM/HDAC2/MRE11/NBN/POLD1/RAD50/RAD51/RAD52/WRN/XRCC2/MLH1/MSH2/MSH6/PMS2/EPCAM/AXIN1/B2M/CD274/EPHA3/ERCC4/FGF19/FGF3/FGF4/KEAP1/MDM4/MTAP/NFE2L2/NOTCH1/NOTCH2/POLE/RNF43/SETD2/ASXL1/CBL/CDC73/CDH1/CDKN1B/CEBPA/CREBBP/DNMT3A/EP300/ERCC3/FAS/FH/FLCN/IKZF1/MAPK1/MEN1/MITF/NKX2-1/PAX5/PRKAR1A/PTPN11/SDHA/SDHB/SDHC/SDHD/SMARCA4/STAT3/SUFU/TERC/WT1/ABL2/ACSL6/ACVR1/ACVR1B/ACVR2A/AFDN/AFF1/AFF3/AKAP9/ALDH2/ALOX12B/AMER1/AR/ARFRP1/ARHGAP5/ARHGEF12/ASXL2/ATP1A1/ATP2B3/AURKA/AURKB/AXIN2/AXL/B3GALT2/BAX/BCL11A/BCL2/BCL2L1/BCL2L12/BCL2L2/BCL3/BCL6/BCL9/BCL9L/BCLAF1/BCOR/BCORL1/BCR/BIRC6/BMP5/BMPR1A/BRD3/BRD4/BTG1/BTG2/BUB1B/CALR/CAMTA1/CARD11/CASP8/CASP9/CBFB/CCDC6/CCR4/CD209/CD22/CD70/CD74/CD79A/CD79B/CDH10/CDH11/CDK8/CDKN1A/CDKN2C/CDX2/CEP43/CEP89/CHD2/CHD4/CIC/CIITA/CLIP1/CLTC/CLTCL1/CNBD1/CNTNAP2/CNTRL/COL1A1/COL2A1/CRKL/CRLF2/CRNKL1/CRTC1/CSMD3/CTCF/CTNNA1/CTNND1/CTNND2/CUL4A/CUX1/CYLD/CYP17A1/DAXX/DCBLD1/DCC/DDB2/DDR1/DDX10/DDX5/DDX6/DGCR8/DICER1/DIS3/DNM2/DNMT1/DOT1L/DROSHA/EBF1/EED/ELL/EML4/EPHA7/EPHB1/EPHB4/EPS15/ERCC5/ERG/ERRFI1/ETV1/ETV6/EVI2A/EVI2B/EXT2/EZR/FAM135B/FAM47C/FAT1/FAT3/FAT4/FBXO11/FCGR2B/FES/FGF10/FGF12/FGF14/FGF23/FGF6/FHIT/FKBP9/FLNA/FLT1/FLT4/FOXA1/FOXL2/FOXO3/FOXP1/FUBP1/GABRA6/GAS7/GATA1/GATA2/GATA3/GATA4/GATA6/GID4/GLI1/GNA13/GNAS/GRIN2A/GRM3/GSK3B/GSTTP2/H3-3A/H3C2/H4C9/HDAC1/HERPUD1/HGF/HIF1A/HIF1A-AS3/HIP1/HLA-A/HLA-B/HLA-C/HMGA1/HNF1A/HNRNPA2B1/HOXA11/HSP90AA1/HSP90AB1/ID3/IGF1R/IKBKE/IL6ST/IL7R/INPP4B/IRF2/IRF4/IRS2/IRS4/ISX/ITGAV/ITK/JUN/KAT6A/KAT6B/KAT7/KCNJ5/KDM5A/KDM5C/KDM6A/KEL/KIAA1549/KLF4/KLHL6/KMT2A/KMT2C/KMT2D/KNL1/KNSTRN/KTN1/LARP4B/LATS1/LATS2/LHFPL6/LMNA/LMO1/LMO2/PTPRK-AS1/LOC645967/LPP/LRIG3/LRP1B/LRRC4/LSM14A/LTK/LYN/LZTR1/MACC1/MAF/MAP2K4/MAP3K13/MAX/MB21D2/MCL1/MECOM/MED12/MEF2B/MERTK/MKNK1/MLH3/MLLT3/MSI2/MSH3/MSN/MST1R/MUC1/MUC16/MUC4/MYB/MYC/MYCL/MYH11/MYOD1/N4BP2/NAB2/NACA/NBEA/NCOA2/NCOR1/NCOR2/NDRG1/NFATC2/NFKB2/NFKBIA/NFKBIE/NIN/NOTCH3/NPIPB2/NPM1/NRG1/NSD1/NSD2/NSD3/NUMA1/NUP214/NUTM2B/OLIG2/P2RY8/PABPC1/PARP1/PARP2/PARP3/PAX3/PBRM1/PCBP1/PCM1/PDCD1/PDCD1LG2/PDE4DIP/PDK1/PER1/PIK3C2B/PIK3C2G/PIK3CB/PIK3R1/PIM1/PLCG1/PMS1/POLQ/PPARG/PPFIBP1/PPM1D/PPP2R1A/PPP6C/PRCC/PRDM1/PRDM2/PREX2/PRKACA/PRKCB/PRKCI/PRKN/PTPN13/PTPN6/PTPRB/PTPRC/PTPRD/PTPRO/PTPRT/QKI/RABEP1/RAC1/RAD21/RANBP2/RARA/RBM10/RBM15/RECQL4/REL/RGPD3/RGS7/RHOA/RICTOR/RIT1/RNF213/ROBO2/RPL10/RPL22/RPL5/RPTOR/RUNX1/RUNX1T1/SALL4/SDC4/SEPTIN9/SETBP1/SETD1B/SETDB1/SF3B1/SGK1/SH2B3/SHTN1/SIRPA/SIX1/SIX2/SLC34A2/SMAD2/SMAD3/SMARCE1/SMC1A/SNCAIP/SNX29/SOCS1/SOX2/SOX9/SPECC1/SPEN/SPOP/SRC/SRSF2/SS18/SSX1/STAG1/STAG2/STAT5B/STAT6/STIL/SYK/TAL2/TAP1/TAP2/TBL1XR1/TBX3/TCEA1/TCF3/TCF7L2/TEC/TEK/TENT5C/TERT/TET1/TET2/TFE3/TFG/THRAP3/TIPARP/TMPRSS2/TNC/TNFAIP3/TNFRSF14/TNFRSF17/TP63/TPR/TRAF7/TRIM24/TRIM33/TRIP11/TRRAP/TSHR/TYRO3/U2AF1/UBR5/USP6/USP8/VEGFA/WAS/WNK2/XPO1/ZEB1/ZFHX3/ZMYM2/ZMYM3/ZNF217/ZNF479/ZNF703/ZNRF3/ZRSR2,MET,TERT,ALK/ATM/B2M/CCND1/CCND2/CCND3/CCNE1/CD274/CDK4/CDKN2A/CDKN2B/CSF1R/EGFR/ERBB2/FGFR1/FGFR2/FGFR3/FLT3/MDM2/MDM4/MET/MYCN/NF2/PTEN/RB1/SMARCB1,ALK/BRAF/FGFR1/FGFR2/FGFR3/MET/NTRK1/NTRK2/NTRK3/PDGFRA/RET/ROS1,BCL2L11,ABCB1/ABCG2/ACYP2/CASP7/CDA/CEP72/CYP19A1/CYP2B6/CYP2D6/CYP3A4/DHFR/DPYD/ERCC1/ERCC2/GSTP1/HAS3/MTHFR/MUTYH/NQO1/NUDT15/PNPLA3/RRM1/SLCO1B1/SLCO1B3/SOD2/TP53/TPMT/TYMS/UGT1A1/XRCC1,ALK/APC/ASXL1/ATM/ATRX/BAP1/BLM/BMPR1A/BRAF/BRCA1/BRCA2/BRIP1/CBL/CDC73/CDH1/CDK4/CDKN1B/CDKN2A/CEBPA/CHEK2/CREBBP/DICER1/DNMT3A/EGFR/EP300/EPCAM/ERCC3/ERCC4/ETV6/FANCA/FANCC/FANCD2/FANCE/FANCG/FANCL/FANCM/FAS/FH/FLCN/GATA2/HRAS/IKZF1/KRAS/LZTR1/MAP2K1/MAP2K2/MAPK1/MEN1/MET/MITF/MLH1/MSH2/MSH3/MSH6/MUTYH/NBN/NF1/NF2/NKX2-1/NRAS/PALB2/PAX5/PMS2/POLD1/POLE/PRKAR1A/PTCH1/PTEN/PTPN11/RAD51/RAD51C/RAD51D/RAF1/RB1/RET/RNF43/RUNX1/SDHA/SDHB/SDHC/SDHD/SMAD4/SMARCA4/SMARCB1/STAT3/STK11/SUFU/TERC/TP53/TSC1/TSC2/VHL/WRN/WT1/XRCC2,MSH2/MSH6/MLH1/PMS2/EPCAM,ATM/ATR/BARD1/BRCA1/BRCA2/BRIP1/CDK12/CHEK1/CHEK2/FANCA/FANCL/MLH1/NBN/PALB2/RAD51B/RAD51C/RAD51D/RAD54L,ARID1A/FANCM/HDAC2/POLD1/PTEN/RAD50/PPP2R2A/ATR/ATRX/BAP1/BLM/FANCA/FANCC/FANCD2/FANCE/FANCG/MRE11/NBN/RAD51/XRCC2/ARID1B/ARID2/EMSY/RAD52/WRN,CCND1/ALK/APC/ARID1A/ATM/ATR/AXIN1/B2M/BAP1/BRCA1/BRCA2/BRIP1/CD274/CDK12/CDKN2A/CDKN2B/CHEK1/CHEK2/CTNNB1/EGFR/EPHA3/ERCC4/FGF19/FGF3/FGF4/JAK1/JAK2/KEAP1/MDM2/MDM4/MRE11/MTAP/NBN/NF1/NFE2L2/NOTCH1/NOTCH2/NTRK3/PALB2/POLD1/POLE/PTEN/RAD50/RAD51C/RAD51D/RNF43/SETD2/SMO/STK11 +LZ102,lung_17_gene,肺癌17基因检测（组织版）,肺癌17基因检测报告（组织版）,addTarget;addFusion;addCnv,ST21,17,ALK/AKT1/BRAF/EGFR/ERBB2/KRAS/MAP2K1/MET/PIK3CA/PTEN/NTRK1/NTRK2/NTRK3/NRAS/RET/ROS1/BCL2L11,MET,NA,ALK/EGFR/ERBB2/MET,ALK/NTRK1/NTRK2/NTRK3/RET/ROS1,BCL2L11,NA,NA,NA,NA,NA,NA +LZ111,lung_17_gene,肺癌17基因检测（血液版）,肺癌17基因检测报告（血液版）,addTarget;addFusion;addCnv,ST21,17,ALK/AKT1/BRAF/EGFR/ERBB2/KRAS/MAP2K1/MET/PIK3CA/PTEN/NTRK1/NTRK2/NTRK3/NRAS/RET/ROS1/BCL2L11,MET,NA,ALK/EGFR/ERBB2/MET,ALK/NTRK1/NTRK2/NTRK3/RET/ROS1,BCL2L11,NA,NA,NA,NA,NA,NA LZ135,lung_85_gene,肺癌85基因检测（组织版）,肺癌85基因检测报告（组织版）,addTarget;addFusion;addCnv;addMsi;addMmr;addChemo,ST21,160,AKT1/ALK/ATM/BARD1/BCL2L11/BRAF/BRCA1/BRCA2/BRIP1/CCND1/CCND2/CDK12/CDK4/CDKN2A/CHEK1/CHEK2/CSF1R/DDR2/EGFR/ERBB2/ERBB4/FANCL/FBXW7/FGFR1/FGFR2/FGFR3/HRAS/IDH1/KIT/KRAS/MET/MTOR/MYC/NF1/NRAS/NTRK1/NTRK2/NTRK3/PALB2/PDGFRA/PIK3CA/PTEN/RAD51B/RAD51C/RAD51D/RAD54L/RET/ROS1/TP53/TSC1/TSC2/VHL/STK11/APC/ARID1A/CTNNB1/EPCAM/ERBB3/MAP2K1/MLH1/MSH2/MSH6/PMS2/RB1/SMAD4/SMO,MET,NA,ALK/CCND1/CCND2/CDK4/CDKN2A/CSF1R/EGFR/ERBB2/FGFR1/FGFR2/FGFR3/MET/MYC/SMO,ALK/NTRK1/NTRK2/NTRK3/RET/ROS1,BCL2L11,ABCB1/CASP7/CDA/CYP2C8/CYP3A4/DPYD/DYNC2H1/ERCC1/ERCC2/GSTP1/MTHFR/NQO1/SOD2/TPMT/TYMS/UGT1A1/XRCC1/XPC/HAS3,NA,MSH2/MSH6/MLH1/PMS2/EPCAM,NA,NA,NA LZ136,lung_85_gene,肺癌85基因检测（血液版）,肺癌85基因检测报告（血液版）,addTarget;addFusion;addCnv;addMmr;addChemo,ST21,160,AKT1/ALK/ATM/BARD1/BCL2L11/BRAF/BRCA1/BRCA2/BRIP1/CCND1/CCND2/CDK12/CDK4/CDKN2A/CHEK1/CHEK2/CSF1R/DDR2/EGFR/ERBB2/ERBB4/FANCL/FBXW7/FGFR1/FGFR2/FGFR3/HRAS/IDH1/KIT/KRAS/MET/MTOR/MYC/NF1/NRAS/NTRK1/NTRK2/NTRK3/PALB2/PDGFRA/PIK3CA/PTEN/RAD51B/RAD51C/RAD51D/RAD54L/RET/ROS1/TP53/TSC1/TSC2/VHL/STK11/APC/ARID1A/CTNNB1/EPCAM/ERBB3/MAP2K1/MLH1/MSH2/MSH6/PMS2/RB1/SMAD4/SMO,MET,NA,ALK/CCND1/CCND2/CDK4/CDKN2A/CSF1R/EGFR/ERBB2/FGFR1/FGFR2/FGFR3/MET/MYC/SMO,ALK/NTRK1/NTRK2/NTRK3/RET/ROS1,BCL2L11,ABCB1/CASP7/CDA/CYP2C8/CYP3A4/DPYD/DYNC2H1/ERCC1/ERCC2/GSTP1/MTHFR/NQO1/SOD2/TPMT/TYMS/UGT1A1/XRCC1/XPC/HAS3,NA,MSH2/MSH6/MLH1/PMS2/EPCAM,NA,NA,NA LZ137,Colorectal_88_gene,结直肠癌88基因检测（组织版）,结直肠癌88基因检测报告（组织版）,addTarget;addFusion;addCnv;addMsi;addMmr;addChemo;addHcs,ST14,160,AKT1/ALK/APC/ARID1A/ATM/BARD1/BRAF/BRCA1/BRCA2/BRIP1/CCND2/CCND3/CDK12/CDK4/CDKN2A/CHEK1/CHEK2/CSF1R/CTNNB1/EGFR/EPCAM/ERBB2/FANCL/FBXW7/FGFR1/FGFR2/FGFR3/FLT3/IDH1/KDR/KIT/KRAS/MAP2K1/MET/MLH1/MSH2/MSH6/MTOR/NF1/NRAS/NTRK1/NTRK2/NTRK3/PALB2/PDGFRA/PIK3CA/PMS2/PTEN/RAD51B/RAD51C/RAD51D/RAD54L/RB1/RET/ROS1/SMAD4/SMO/TP53/TSC1/TSC2/VHL/POLD1/POLE/STK11/MUTYH/SDHA/SDHB/SDHC/SDHD,MET,NA,ALK/CCND2/CCND3/CDK4/CDKN2A/CSF1R/EGFR/ERBB2/FGFR1/FGFR2/FGFR3/FLT3/MET/PTEN/RB1,ALK/NTRK1/NTRK2/NTRK3/RET/ROS1,NA,ABCB1/CASP7/CDA/CYP2C8/CYP3A4/DPYD/DYNC2H1/ERCC1/ERCC2/GSTP1/MTHFR/NQO1/SOD2/TPMT/TYMS/UGT1A1/XRCC1/XPC/HAS3,MLH1/MSH2/MSH6/PMS2/EPCAM/TP53/APC/MUTYH/SMAD4/STK11/PTEN,MSH2/MSH6/MLH1/PMS2/EPCAM,NA,NA,NA