更新数据库

codes/filter_snpindel.pl

@@ -262,14 +262,28 @@ while (<IN>) {
     }
 
     my $clisig;
-    if ($line[16] =~ /Likely_pathogenic|drug/i) {
+    # somatic 依据oncogenic改变等级
-        $clisig = '2';
+    if (($pipeline eq 'somatic') | ($pipeline eq 'hotspot')) {
-    }
+        if ($oncogenic_col =~ /Likely Oncogenic/i) {
-    elsif ($line[16] =~ /pathogenic/i and $line[16] !~ /Conflicting/i) {
+            $clisig = '2';
-        $clisig = '1';
+        }
+        elsif ($oncogenic_col =~ /Oncogenic/i) {
+            $clisig = '1';
+        }
+        else {
+            $clisig = '3';
+        }
     }
     else {
-        $clisig = '3';
+        if ($line[16] =~ /Likely_pathogenic|drug/i) {
+            $clisig = '2';
+        }
+        elsif ($line[16] =~ /pathogenic/i and $line[16] !~ /Conflicting/i) {
+            $clisig = '1';
+        }
+        else {
+            $clisig = '3';
+        }
     }
 
     my @genetags;

codes/public/blacklist.txt

@@ -19,3 +19,5 @@ chr6	31238909	31238910	GT	TC	HLA-C	p.T187E
 chr3	10088407	10088410	AGTA	-	FANCD2	p.V427Ffs*20
 chr12	57112003	57112003	A	G	NACA	p.M1104T
 chr12	57112022	57112022	A	G	NACA	p.S1098P
+chr22	44324727	44324730	CCCC	GCCT	PNPLA3	p.I148M
+chr7	116397716	116397716	C	G	MET	p.P664A

database/cnv.csv

@@ -1,249 +1,262 @@
-Gene,Alteration,Oncogenic,Mutation_Effect,Citations
+Gene,Alteration,Oncogenic,Mutation_Effect,Citations
-CDK6,Amplification,Oncogenic,Gain-of-function,4
+CDK6,Amplification,Oncogenic,Gain-of-function,4
-MCL1,Amplification,Oncogenic,Gain-of-function,4
+MCL1,Amplification,Oncogenic,Gain-of-function,4
-PDGFRA,Amplification,Oncogenic,Gain-of-function,4
+PDGFRA,Amplification,Oncogenic,Gain-of-function,4
-SRC,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+SRC,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-FGFR4,Amplification,Oncogenic,Gain-of-function,4
+FGFR4,Amplification,Oncogenic,Gain-of-function,4
-ECSIT,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+ECSIT,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-EGFR,Amplification,Oncogenic,Gain-of-function,4
+EGFR,Amplification,Oncogenic,Gain-of-function,4
-HRAS,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+HRAS,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-ERCC2,Amplification,Inconclusive,Inconclusive,4
+ERCC2,Amplification,Inconclusive,Inconclusive,4
-ATP1A1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+ATP1A1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-UBR5,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+UBR5,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,Amplification,Inconclusive,Inconclusive,4
+PDGFRB,Amplification,Inconclusive,Inconclusive,4
-MYC,Amplification,Oncogenic,Gain-of-function,4
+MYC,Amplification,Oncogenic,Gain-of-function,4
-CDK4,Amplification,Oncogenic,Gain-of-function,4
+CDK4,Amplification,Oncogenic,Gain-of-function,4
-RICTOR,Amplification,Oncogenic,Gain-of-function,4
+RICTOR,Amplification,Oncogenic,Gain-of-function,4
-ALK,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+ALK,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-PHF19,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+PHF19,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-RAC1,Amplification,Likely Oncogenic,Gain-of-function,4
+RAC1,Amplification,Likely Oncogenic,Gain-of-function,4
-CARD11,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+CARD11,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-AXL,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+AXL,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-FGFR1,Amplification,Oncogenic,Gain-of-function,4
+FGFR1,Amplification,Oncogenic,Gain-of-function,4
-PIK3R2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+PIK3R2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-KAT7,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+KAT7,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-GLI1,Amplification,Oncogenic,Gain-of-function,4
+GLI1,Amplification,Oncogenic,Gain-of-function,4
-NRAS,Amplification,Inconclusive,Inconclusive,4
+NRAS,Amplification,Inconclusive,Inconclusive,4
-CXCR4,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+CXCR4,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-PSMB2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+PSMB2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-BRAF,Amplification,Oncogenic,Gain-of-function,4
+BRAF,Amplification,Oncogenic,Gain-of-function,4
-FLT1,Amplification,Inconclusive,Inconclusive,4
+FLT1,Amplification,Inconclusive,Inconclusive,4
-DNMT3B,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+DNMT3B,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-KDM5A,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+KDM5A,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-AR,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+AR,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-MDM2,Amplification,Oncogenic,Gain-of-function,4
+MDM2,Amplification,Oncogenic,Gain-of-function,4
-YES1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+YES1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-FOXA1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+FOXA1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-MERTK,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+MERTK,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-MAP2K1,Amplification,Inconclusive,Inconclusive,4
+MAP2K1,Amplification,Inconclusive,Inconclusive,4
-MYCL,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+MYCL,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-PPM1D,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+PPM1D,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-NKX2-1,Amplification,Oncogenic,Gain-of-function,4
+NKX2-1,Amplification,Oncogenic,Gain-of-function,4
-MYCN,Amplification,Oncogenic,Gain-of-function,4
+MYCN,Amplification,Oncogenic,Gain-of-function,4
-ERBB3,Amplification,Oncogenic,Gain-of-function,4
+ERBB3,Amplification,Oncogenic,Gain-of-function,4
-ETV1,Amplification,Oncogenic,Gain-of-function,4
+ETV1,Amplification,Oncogenic,Gain-of-function,4
-SETD3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+SETD3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-ERBB2,Amplification,Oncogenic,Gain-of-function,4
+ERBB2,Amplification,Oncogenic,Gain-of-function,4
-ROS1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+ROS1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-AURKA,Amplification,Oncogenic,Gain-of-function,4
+AURKA,Amplification,Oncogenic,Gain-of-function,4
-NTRK1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+NTRK1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-ACKR3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+ACKR3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-MDM4,Amplification,Oncogenic,Gain-of-function,4
+MDM4,Amplification,Oncogenic,Gain-of-function,4
-GATA3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+GATA3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-BCL6,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+BCL6,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-JUN,Amplification,Oncogenic,Gain-of-function,4
+JUN,Amplification,Oncogenic,Gain-of-function,4
-RNASEH2A,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+RNASEH2A,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-REV3L,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+REV3L,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-PAK1,Amplification,Oncogenic,Gain-of-function,4
+PAK1,Amplification,Oncogenic,Gain-of-function,4
-CCND3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+CCND3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-FGF4,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+FGF4,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-PIK3CB,Amplification,Likely Oncogenic,Gain-of-function,4
+PIK3CB,Amplification,Likely Oncogenic,Gain-of-function,4
-GAB2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+GAB2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-KIT,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+KIT,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-RHOA,Amplification,Oncogenic,Gain-of-function,4
+RHOA,Amplification,Oncogenic,Gain-of-function,4
-RAF1,Amplification,Oncogenic,Gain-of-function,4
+RAF1,Amplification,Oncogenic,Gain-of-function,4
-CCND1,Amplification,Oncogenic,Gain-of-function,4
+CCND1,Amplification,Oncogenic,Gain-of-function,4
-ESR1,Amplification,Inconclusive,Inconclusive,4
+ESR1,Amplification,Inconclusive,Inconclusive,4
-BAALC,Amplification,Likely Oncogenic,Likely Gain-of-function,3
+BAALC,Amplification,Likely Oncogenic,Likely Gain-of-function,3
-ID1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+ID1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-KDR,Amplification,Oncogenic,Gain-of-function,4
+KDR,Amplification,Oncogenic,Gain-of-function,4
-PIK3CA,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+PIK3CA,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-MEF2B,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+MEF2B,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-JAK2,Amplification,Oncogenic,Gain-of-function,4
+JAK2,Amplification,Oncogenic,Gain-of-function,4
-FGF3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+FGF3,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-MAPK1,Amplification,Likely Oncogenic,Gain-of-function,4
+MAPK1,Amplification,Likely Oncogenic,Gain-of-function,4
-CD274,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+CD274,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-MET,Amplification,Oncogenic,Gain-of-function,4
+MET,Amplification,Oncogenic,Gain-of-function,4
-FUS,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+FUS,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-FZR1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+FZR1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-YAP1,Amplification,Oncogenic,Gain-of-function,4
+YAP1,Amplification,Oncogenic,Gain-of-function,4
-CCNE1,Amplification,Oncogenic,Gain-of-function,4
+CCNE1,Amplification,Oncogenic,Gain-of-function,4
-CRLF2,Amplification,Oncogenic,Gain-of-function,4
+CRLF2,Amplification,Oncogenic,Gain-of-function,4
-NSD3,Amplification,Inconclusive,Inconclusive,4
+NSD3,Amplification,Inconclusive,Inconclusive,4
-VEGFA,Amplification,Likely Oncogenic,Gain-of-function,4
+VEGFA,Amplification,Likely Oncogenic,Gain-of-function,4
-SMO,Amplification,Inconclusive,Inconclusive,4
+SMO,Amplification,Inconclusive,Inconclusive,4
-KRAS,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+KRAS,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-ADHFE1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+ADHFE1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-IKBKE,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+IKBKE,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-RHEB,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+RHEB,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-ALOX12B,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+ALOX12B,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-BCL2L1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+BCL2L1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-BRD4,Amplification,Likely Oncogenic,Gain-of-function,4
+BRD4,Amplification,Likely Oncogenic,Gain-of-function,4
-FGF19,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+FGF19,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-TOP1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+TOP1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-KMT2A,Amplification,Inconclusive,Inconclusive,4
+KMT2A,Amplification,Inconclusive,Inconclusive,4
-RUNX1,Amplification,Oncogenic,Gain-of-function,4
+RUNX1,Amplification,Oncogenic,Gain-of-function,4
-AGO2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+AGO2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-DDR2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+DDR2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-AKT1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+AKT1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-HMGA1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+HMGA1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-TRIM27,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+TRIM27,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-CYP19A1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+CYP19A1,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-IRS2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+IRS2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-PAX5,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+PAX5,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-LGR5,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+LGR5,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-CDK8,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+CDK8,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-AKT2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+AKT2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-HMGA2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+HMGA2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-CDK12,Amplification,Inconclusive,Inconclusive,4
+CDK12,Amplification,Inconclusive,Inconclusive,4
-MITF,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+MITF,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-PDCD1LG2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+PDCD1LG2,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-EZH2,Amplification,Oncogenic,Gain-of-function,4
+EZH2,Amplification,Oncogenic,Gain-of-function,4
-AKT3,Amplification,Oncogenic,Gain-of-function,4
+AKT3,Amplification,Oncogenic,Gain-of-function,4
-TERT,Amplification,Likely Oncogenic,Likely Gain-of-function,4
+TERT,Amplification,Likely Oncogenic,Likely Gain-of-function,4
-KDM5C,Overexpression,Likely Oncogenic,Likely Gain-of-function,4
+KDM5C,Overexpression,Likely Oncogenic,Likely Gain-of-function,4
-AURKB,Overexpression,Likely Oncogenic,Likely Gain-of-function,4
+AURKB,Overexpression,Likely Oncogenic,Likely Gain-of-function,4
-RHOA,Overexpression,Oncogenic,Gain-of-function,4
+RHOA,Overexpression,Oncogenic,Gain-of-function,4
-CCNE1,Overexpression,Oncogenic,Gain-of-function,4
+CCNE1,Overexpression,Oncogenic,Gain-of-function,4
-EZH2,Overexpression,Oncogenic,Gain-of-function,4
+EZH2,Overexpression,Oncogenic,Gain-of-function,4
-MSH2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+MSH2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-BBC3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+BBC3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-EP300,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+EP300,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-CHTF8,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+CHTF8,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-ATRIP,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+ATRIP,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-BAP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+BAP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-TGFBR1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+TGFBR1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-MSH3,Deletion,Likely Oncogenic,Loss-of-function,4
+MSH3,Deletion,Likely Oncogenic,Loss-of-function,4
-DAXX,Deletion,Oncogenic,Loss-of-function,4
+DAXX,Deletion,Oncogenic,Loss-of-function,4
-DUSP4,Deletion,Inconclusive,Inconclusive,4
+DUSP4,Deletion,Inconclusive,Inconclusive,4
-FANCA,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+FANCA,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-ERRFI1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+ERRFI1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-BRIP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+BRIP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-PTPRD,Deletion,Oncogenic,Loss-of-function,4
+PTPRD,Deletion,Oncogenic,Loss-of-function,4
-TGFBR2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+TGFBR2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-CTCF,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+CTCF,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-NF1,Deletion,Likely Oncogenic,Loss-of-function,4
+NF1,Deletion,Likely Oncogenic,Loss-of-function,4
-FBXW7,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+FBXW7,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-RAD51B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+RAD51B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-ATM,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+ATM,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-MLH1,Deletion,Likely Oncogenic,Loss-of-function,4
+MLH1,Deletion,Likely Oncogenic,Loss-of-function,4
-BTG1,Deletion,Likely Oncogenic,Loss-of-function,4
+BTG1,Deletion,Likely Oncogenic,Loss-of-function,4
-RELN,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+RELN,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-NOTCH1,Deletion,Likely Oncogenic,Likely Gain-of-function,4
+NOTCH1,Deletion,Likely Oncogenic,Likely Gain-of-function,4
-PIK3R1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+PIK3R1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-XRCC2,Deletion,Likely Neutral,Likely Loss-of-function,4
+XRCC2,Deletion,Likely Neutral,Likely Loss-of-function,4
-ERCC4,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+ERCC4,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-NF2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+NF2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-CIITA,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+CIITA,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-SOX17,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+SOX17,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-MSH6,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+MSH6,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-HNF1A,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+HNF1A,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-BRCA2,Deletion,Oncogenic,Loss-of-function,4
+BRCA2,Deletion,Oncogenic,Loss-of-function,4
-BCOR,Deletion,Oncogenic,Loss-of-function,4
+BCOR,Deletion,Oncogenic,Loss-of-function,4
-ATRX,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+ATRX,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-DNMT3A,Deletion,Oncogenic,Loss-of-function,4
+DNMT3A,Deletion,Oncogenic,Loss-of-function,4
-CDKN2B,Deletion,Oncogenic,Loss-of-function,4
+CDKN2B,Deletion,Oncogenic,Loss-of-function,4
-PMS2,Deletion,Oncogenic,Loss-of-function,4
+PMS2,Deletion,Oncogenic,Loss-of-function,4
-PARP1,Deletion,Likely Oncogenic,Loss-of-function,4
+PARP1,Deletion,Likely Oncogenic,Loss-of-function,4
-CDKN2C,Deletion,Oncogenic,Loss-of-function,4
+CDKN2C,Deletion,Oncogenic,Loss-of-function,4
-RAD17,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+RAD17,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-CD58,Deletion,Likely Oncogenic,Loss-of-function,4
+CD58,Deletion,Likely Oncogenic,Loss-of-function,4
-EED,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+EED,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-TP53BP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+TP53BP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-BRCA1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+BRCA1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-MED12,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+MED12,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-SMARCA4,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+SMARCA4,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-CDKN2A,Deletion,Oncogenic,Loss-of-function,4
+CDKN2A,Deletion,Oncogenic,Loss-of-function,4
-DNMT3B,Deletion,Likely Oncogenic,Loss-of-function,4
+DNMT3B,Deletion,Likely Oncogenic,Loss-of-function,4
-NPM1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+NPM1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-SOX9,Deletion,Oncogenic,Loss-of-function,4
+SOX9,Deletion,Oncogenic,Loss-of-function,4
-APC,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+APC,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-BCL2L11,Deletion,Oncogenic,Likely Loss-of-function,4
+BCL2L11,Deletion,Oncogenic,Likely Loss-of-function,4
-CIC,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+CIC,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-SHQ1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+SHQ1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-RBM10,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+RBM10,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-AXIN1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+AXIN1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-FOXA1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+FOXA1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-PBRM1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+PBRM1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-EPHA3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+EPHA3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-VHL,Deletion,Oncogenic,Likely Loss-of-function,4
+VHL,Deletion,Oncogenic,Likely Loss-of-function,4
-BCL10,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+BCL10,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-KEAP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+KEAP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-CDC73,Deletion,Oncogenic,Loss-of-function,4
+CDC73,Deletion,Oncogenic,Loss-of-function,4
-COP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+COP1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-CASP8,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+CASP8,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-PTEN,Deletion,Oncogenic,Loss-of-function,4
+PTEN,Deletion,Oncogenic,Loss-of-function,4
-SETD2,Deletion,Oncogenic,Loss-of-function,4
+SETD2,Deletion,Oncogenic,Loss-of-function,4
-MGA,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+MGA,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-STK11,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+STK11,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-ALDH2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+ALDH2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-TET2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+TET2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-GATA3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+GATA3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-TP53,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+TP53,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-REV3L,Deletion,Inconclusive,Inconclusive,4
+REV3L,Deletion,Inconclusive,Inconclusive,4
-SDHB,Deletion,Likely Oncogenic,Loss-of-function,4
+SDHB,Deletion,Likely Oncogenic,Loss-of-function,4
-INPP4B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+INPP4B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-LATS1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+LATS1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-TET1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+TET1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-RNASEH2B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+RNASEH2B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-PTPN11,Deletion,Oncogenic,Loss-of-function,4
+PTPN11,Deletion,Oncogenic,Loss-of-function,4
-SMARCB1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+SMARCB1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-CREBBP,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+CREBBP,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-RAD21,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+RAD21,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-LATS2,Deletion,Oncogenic,Loss-of-function,4
+LATS2,Deletion,Oncogenic,Loss-of-function,4
-ASXL2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+ASXL2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-CDKN1A,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+CDKN1A,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-KDM6A,Deletion,Oncogenic,Loss-of-function,4
+KDM6A,Deletion,Oncogenic,Loss-of-function,4
-SDHD,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+SDHD,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-ARID1A,Deletion,Likely Oncogenic,Loss-of-function,4
+ARID1A,Deletion,Likely Oncogenic,Loss-of-function,4
-FZR1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+FZR1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-ASXL1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+ASXL1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-CDKN1B,Deletion,Oncogenic,Loss-of-function,4
+CDKN1B,Deletion,Oncogenic,Loss-of-function,4
-TNFAIP3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+TNFAIP3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-ARID1B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+ARID1B,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-IKZF1,Deletion,Likely Oncogenic,Loss-of-function,4
+IKZF1,Deletion,Likely Oncogenic,Loss-of-function,4
-KMT2C,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+KMT2C,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-MAX,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+MAX,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-CBL,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+CBL,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-FH,Deletion,Likely Oncogenic,Loss-of-function,4
+FH,Deletion,Likely Oncogenic,Loss-of-function,4
-RB1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+RB1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-PPP2R2A,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+PPP2R2A,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-MTAP,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+MTAP,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-SMAD4,Deletion,Likely Oncogenic,Loss-of-function,4
+SMAD4,Deletion,Likely Oncogenic,Loss-of-function,4
-CDH1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+CDH1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-BARD1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+BARD1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-TSC2,Deletion,Oncogenic,Likely Loss-of-function,4
+TSC2,Deletion,Oncogenic,Likely Loss-of-function,4
-KMT2D,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+KMT2D,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-HTATIP2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+HTATIP2,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-RASA1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+RASA1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-MEN1,Deletion,Oncogenic,Loss-of-function,4
+MEN1,Deletion,Oncogenic,Loss-of-function,4
-PAX5,Deletion,Likely Oncogenic,Loss-of-function,4
+PAX5,Deletion,Likely Oncogenic,Loss-of-function,4
-BCL11B,Deletion,Likely Oncogenic,Loss-of-function,4
+BCL11B,Deletion,Likely Oncogenic,Loss-of-function,4
-B2M,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+B2M,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-SMAD3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+SMAD3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-INTS6,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+INTS6,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-CDK12,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+CDK12,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-TSC1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+TSC1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-BIRC3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+BIRC3,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-RAD50,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+RAD50,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-FAT1,Deletion,Oncogenic,Loss-of-function,4
+FAT1,Deletion,Oncogenic,Loss-of-function,4
-SMAD2,Deletion,Likely Oncogenic,Loss-of-function,4
+SMAD2,Deletion,Likely Oncogenic,Loss-of-function,4
-ANKRD11,Deletion,Likely Oncogenic,Loss-of-function,4
+ANKRD11,Deletion,Likely Oncogenic,Loss-of-function,4
-DICER1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+DICER1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-SETD3,Overexpression,Likely Oncogenic,Likely Gain-of-function,1
+SETD3,Overexpression,Likely Oncogenic,Likely Gain-of-function,1
-CRLF2,Overexpression,Oncogenic,Gain-of-function,10
+CRLF2,Overexpression,Oncogenic,Gain-of-function,10
-FLT3,Amplification,Likely Oncogenic,Gain-of-function,2
+FLT3,Amplification,Likely Oncogenic,Gain-of-function,2
-PRDM1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
+PRDM1,Deletion,Likely Oncogenic,Likely Loss-of-function,4
-TLE1,Deletion,Likely Oncogenic,Likely Loss-of-function,2
+TLE1,Deletion,Likely Oncogenic,Likely Loss-of-function,2
-TLE4,Deletion,Likely Oncogenic,Likely Loss-of-function,2
+TLE4,Deletion,Likely Oncogenic,Likely Loss-of-function,2
+CCND2,Amplification,Likely Oncogenic,Likely Gain-of-function,3
+FGFR3,Amplification,Likely Oncogenic,Likely Gain-of-function,.
+MMS22L,Deletion,Likely Oncogenic,Likely Loss-of-function,.
+CHEK2,Deletion,Likely Oncogenic,Likely Loss-of-function,.
+DPAGT1,Amplification,Likely Oncogenic,Likely Gain-of-function,1
+HGF,Amplification,Likely Oncogenic,Likely Gain-of-function,.
+NTRK2,Amplification,Likely Oncogenic,Likely Gain-of-function,
+NTRK3,Amplification,Likely Oncogenic,Likely Gain-of-function,
+CSF1R,Amplification,Likely Oncogenic,Likely Gain-of-function,1
+TLK2,Amplification,Likely Oncogenic,Likely Gain-of-function,1
+RIT1,Amplification,Likely Oncogenic,Likely Gain-of-function,3
+CRKL,Amplification,Likely Oncogenic,Likely Gain-of-function,2
+FLT3,Amplification,Likely Oncogenic,Likely Gain-of-function,.

database/fusion.csv

@@ -1,339 +1,340 @@
-Gene,Alteration,Oncogenic,Mutation_Effect,Citations
+Gene,Alteration,Oncogenic,Mutation_Effect,Citations
-EP300,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+EP300,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-EP300,MLL-EP300 Fusion,Inconclusive,Inconclusive,4
+EP300,MLL-EP300 Fusion,Inconclusive,Inconclusive,4
-EP300,MOZ-EP300 Fusion,Likely Oncogenic,Gain-of-function,4
+EP300,MOZ-EP300 Fusion,Likely Oncogenic,Gain-of-function,4
-TCL1B,TRA-TCL1B Fusion,Oncogenic,Likely Gain-of-function,4
+TCL1B,TRA-TCL1B Fusion,Oncogenic,Likely Gain-of-function,4
-PDGFRA,STRN-PDGFRA Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRA,STRN-PDGFRA Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRA,FIP1L1-PDGFRA Fusion,Oncogenic,Gain-of-function,4
+PDGFRA,FIP1L1-PDGFRA Fusion,Oncogenic,Gain-of-function,4
-PDGFRA,KDR-PDGFRA Fusion,Oncogenic,Gain-of-function,4
+PDGFRA,KDR-PDGFRA Fusion,Oncogenic,Gain-of-function,4
-PDGFRA,BCR-PDGFRA Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRA,BCR-PDGFRA Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRA,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRA,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRA,ETV6-PDGFRA Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRA,ETV6-PDGFRA Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRA,CDK5RAP2-PDGFRA Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRA,CDK5RAP2-PDGFRA Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRA,KIF5B-PDGFRA Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRA,KIF5B-PDGFRA Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MAF,IGH-MAF Fusion,Oncogenic,Likely Gain-of-function,4
+MAF,IGH-MAF Fusion,Oncogenic,Likely Gain-of-function,4
-NRG1,SLC3A2-NRG1 fusion,Oncogenic,Gain-of-function,4
+NRG1,SLC3A2-NRG1 fusion,Oncogenic,Gain-of-function,4
-NRG1,APP-NRG1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NRG1,APP-NRG1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NRG1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NRG1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NRG1,ATP1B1-NRG1 fusion,Oncogenic,Gain-of-function,4
+NRG1,ATP1B1-NRG1 fusion,Oncogenic,Gain-of-function,4
-NRG1,CD74-NRG1 fusion,Oncogenic,Gain-of-function,4
+NRG1,CD74-NRG1 fusion,Oncogenic,Gain-of-function,4
-DDIT3,FUS-DDIT3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+DDIT3,FUS-DDIT3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-DDIT3,EWSR1-DDIT3 Fusion,Oncogenic,Gain-of-function,4
+DDIT3,EWSR1-DDIT3 Fusion,Oncogenic,Gain-of-function,4
-TLX3,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+TLX3,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-IL3,IGH-IL3 Fusion,Oncogenic,Gain-of-function,4
+IL3,IGH-IL3 Fusion,Oncogenic,Gain-of-function,4
-EGFR,HMGA2-EGFR Fusion,Likely Oncogenic,Likely Gain-of-function,4
+EGFR,HMGA2-EGFR Fusion,Likely Oncogenic,Likely Gain-of-function,4
-EGFR,EGFR-RAD51 Fusion,Oncogenic,Gain-of-function,4
+EGFR,EGFR-RAD51 Fusion,Oncogenic,Gain-of-function,4
-EGFR,EGFR-SEPT14 Fusion,Oncogenic,Gain-of-function,4
+EGFR,EGFR-SEPT14 Fusion,Oncogenic,Gain-of-function,4
-TLX1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+TLX1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-TCL1A,TRA-TCL1A Fusion,Oncogenic,Likely Gain-of-function,4
+TCL1A,TRA-TCL1A Fusion,Oncogenic,Likely Gain-of-function,4
-CBFB,CBFB-MYH11 Fusion,Likely Oncogenic,Likely Loss-of-function,4
+CBFB,CBFB-MYH11 Fusion,Likely Oncogenic,Likely Loss-of-function,4
-PDGFRB,TP53BP1-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,TP53BP1-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,KANK1-PDGFRB Fusion,Oncogenic,Gain-of-function,4
+PDGFRB,KANK1-PDGFRB Fusion,Oncogenic,Gain-of-function,4
-PDGFRB,PRKG2-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,PRKG2-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,GIT2-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,GIT2-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,PDE4DIP-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,PDE4DIP-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,BIN2-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,BIN2-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,HIP1-PDGFRB Fusion,Oncogenic,Gain-of-function,4
+PDGFRB,HIP1-PDGFRB Fusion,Oncogenic,Gain-of-function,4
-PDGFRB,GPIAP1-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,GPIAP1-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,WDR48-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,WDR48-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,SPTBN1-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,SPTBN1-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,RABEP1-PDGFRB Fusion,Oncogenic,Gain-of-function,4
+PDGFRB,RABEP1-PDGFRB Fusion,Oncogenic,Gain-of-function,4
-PDGFRB,AGGF1-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,AGGF1-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,KIAA1509-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,KIAA1509-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,CEP85L-PDGFRB Fusion,Oncogenic,Likely Gain-of-function,4
+PDGFRB,CEP85L-PDGFRB Fusion,Oncogenic,Likely Gain-of-function,4
-PDGFRB,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,ATF7IP-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,ATF7IP-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,EBF1-PDGFRB Fusion,Oncogenic,Gain-of-function,4
+PDGFRB,EBF1-PDGFRB Fusion,Oncogenic,Gain-of-function,4
-PDGFRB,GOLGA4-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,GOLGA4-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFRB,ETV6-PDGFRB Fusion,Oncogenic,Gain-of-function,4
+PDGFRB,ETV6-PDGFRB Fusion,Oncogenic,Gain-of-function,4
-PDGFRB,NIN-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PDGFRB,NIN-PDGFRB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MLLT3,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MLLT3,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MYC,PVT1-MYC Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MYC,PVT1-MYC Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MYC,IGH-MYC Fusion,Oncogenic,Gain-of-function,4
+MYC,IGH-MYC Fusion,Oncogenic,Gain-of-function,4
-MYC,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MYC,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MYC,IGK-MYC Fusion,Oncogenic,Gain-of-function,4
+MYC,IGK-MYC Fusion,Oncogenic,Gain-of-function,4
-MYC,IGL-MYC Fusion,Oncogenic,Gain-of-function,4
+MYC,IGL-MYC Fusion,Oncogenic,Gain-of-function,4
-FGFR3,IGH-FGFR3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR3,IGH-FGFR3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR3,FGFR3-BAIAP2L1 Fusion,Oncogenic,Gain-of-function,4
+FGFR3,FGFR3-BAIAP2L1 Fusion,Oncogenic,Gain-of-function,4
-FGFR3,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR3,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR3,FGFR3-TACC3 Fusion,Oncogenic,Gain-of-function,4
+FGFR3,FGFR3-TACC3 Fusion,Oncogenic,Gain-of-function,4
-RAD51B,HMGA2-RAD51B Fusion,Likely Oncogenic,Likely Loss-of-function,4
+RAD51B,HMGA2-RAD51B Fusion,Likely Oncogenic,Likely Loss-of-function,4
-ALK,ALK-GCC2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ALK,ALK-GCC2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ALK,RANBP2-ALK Fusion,Oncogenic,Gain-of-function,4
+ALK,RANBP2-ALK Fusion,Oncogenic,Gain-of-function,4
-ALK,NPM1-ALK Fusion,Oncogenic,Gain-of-function,4
+ALK,NPM1-ALK Fusion,Oncogenic,Gain-of-function,4
-ALK,ALK-ITGAV Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ALK,ALK-ITGAV Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ALK,ALK-DYSF Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ALK,ALK-DYSF Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ALK,CAD-ALK Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ALK,CAD-ALK Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ALK,EML4-ALK Fusion,Oncogenic,Gain-of-function,4
+ALK,EML4-ALK Fusion,Oncogenic,Gain-of-function,4
-ALK,STRN-ALK Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ALK,STRN-ALK Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ALK,KIF5B-ALK Fusion,Likely Oncogenic,Gain-of-function,4
+ALK,KIF5B-ALK Fusion,Likely Oncogenic,Gain-of-function,4
-ALK,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ALK,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,FGFR2-ZMYM4 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,FGFR2-ZMYM4 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,FGFR2-OPTN Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,FGFR2-OPTN Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,KLK2-FGFR2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,KLK2-FGFR2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,FGFR2-MGEA5 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,FGFR2-MGEA5 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,FGFR2-TACC3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,FGFR2-TACC3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,FGFR2-PPHLN1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,FGFR2-PPHLN1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,FGFR2-KIAA1598 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,FGFR2-KIAA1598 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,FGFR2-BICC1 Fusion,Oncogenic,Gain-of-function,4
+FGFR2,FGFR2-BICC1 Fusion,Oncogenic,Gain-of-function,4
-FGFR2,FGFR2-ATE1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,FGFR2-ATE1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,FGFR2-TACC2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,FGFR2-TACC2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,FGFR2-AHCYL1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,FGFR2-AHCYL1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,FGFR2-CIT Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,FGFR2-CIT Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,FGFR2-CCDC6 Fusion,Likely Oncogenic,Gain-of-function,4
+FGFR2,FGFR2-CCDC6 Fusion,Likely Oncogenic,Gain-of-function,4
-FGFR2,FGFR2-KIAA1967 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,FGFR2-KIAA1967 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR2,FGFR2-FAM76A Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR2,FGFR2-FAM76A Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NOTCH1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NOTCH1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NOTCH1,MIR143-NOTCH1 Fusion,Inconclusive,Inconclusive,4
+NOTCH1,MIR143-NOTCH1 Fusion,Inconclusive,Inconclusive,4
-NOTCH1,SEC16A-NOTCH1 Fusion,Oncogenic,Gain-of-function,4
+NOTCH1,SEC16A-NOTCH1 Fusion,Oncogenic,Gain-of-function,4
-FEV,EWSR1-FEV Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FEV,EWSR1-FEV Fusion,Likely Oncogenic,Likely Gain-of-function,4
-CIITA,Fusion,Likely Oncogenic,Likely Loss-of-function,4
+CIITA,Fusion,Likely Oncogenic,Likely Loss-of-function,4
-CIITA,CIITA-BX648577 Fusion,Likely Oncogenic,Likely Loss-of-function,4
+CIITA,CIITA-BX648577 Fusion,Likely Oncogenic,Likely Loss-of-function,4
-CIITA,NUBP1-CIITA Fusion,Likely Oncogenic,Loss-of-function,4
+CIITA,NUBP1-CIITA Fusion,Likely Oncogenic,Loss-of-function,4
-FGFR1,ERLIN2-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,4
+FGFR1,ERLIN2-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,4
-FGFR1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR1,ZMYM2-FGFR1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR1,ZMYM2-FGFR1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR1,BAG4-FGFR1 Fusion,Likely Neutral,Likely Loss-of-function,4
+FGFR1,BAG4-FGFR1 Fusion,Likely Neutral,Likely Loss-of-function,4
-FGFR1,CEP110-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,4
+FGFR1,CEP110-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,4
-FGFR1,CNTRL-FGFR1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FGFR1,CNTRL-FGFR1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FGFR1,FGFR1OP-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,4
+FGFR1,FGFR1OP-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,4
-FGFR1,ZNF198-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,4
+FGFR1,ZNF198-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,4
-FGFR1,BCR-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,4
+FGFR1,BCR-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,4
-FGFR1,CUX1-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,4
+FGFR1,CUX1-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,4
-EPOR,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+EPOR,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ABL2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ABL2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-KAT6A,KAT6A-TIF2 Fusion,Oncogenic,Gain-of-function,4
+KAT6A,KAT6A-TIF2 Fusion,Oncogenic,Gain-of-function,4
-MECOM,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MECOM,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MECOM,GATA2-MECOM Fusion,Oncogenic,Gain-of-function,4
+MECOM,GATA2-MECOM Fusion,Oncogenic,Gain-of-function,4
-TRG,Fusion,Likely Oncogenic,Likely Gain-of-function,2
+TRG,Fusion,Likely Oncogenic,Likely Gain-of-function,2
-ETV5,TMPRSS2-ETV5 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ETV5,TMPRSS2-ETV5 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-SS18,SS18-SSX1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+SS18,SS18-SSX1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-SS18,SS18-SSX2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+SS18,SS18-SSX2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-SQSTM1,SQSTM1-NUP214 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+SQSTM1,SQSTM1-NUP214 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ETV4,TMPRSS2-ETV4 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ETV4,TMPRSS2-ETV4 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ETV4,EWSR1-ETV4 Fusion,Likely Oncogenic,Gain-of-function,4
+ETV4,EWSR1-ETV4 Fusion,Likely Oncogenic,Gain-of-function,4
-FLT3,ETV6-FLT3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FLT3,ETV6-FLT3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-VAV1,VAV1-S100A7 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+VAV1,VAV1-S100A7 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-VAV1,VAV1-MYO1F Fusion,Likely Oncogenic,Likely Gain-of-function,4
+VAV1,VAV1-MYO1F Fusion,Likely Oncogenic,Likely Gain-of-function,4
-VAV1,VAV1-THAP4 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+VAV1,VAV1-THAP4 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ABL1,NUP214-ABL1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ABL1,NUP214-ABL1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ABL1,BCR-ABL1 Fusion,Oncogenic,Gain-of-function,4
+ABL1,BCR-ABL1 Fusion,Oncogenic,Gain-of-function,4
-ABL1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ABL1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BRAF,ARMC10-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BRAF,ARMC10-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BRAF,TRIM24-BRAF Fusion,Likely Oncogenic,Gain-of-function,4
+BRAF,TRIM24-BRAF Fusion,Likely Oncogenic,Gain-of-function,4
-BRAF,FAM131B-BRAF Fusion,Likely Oncogenic,Gain-of-function,4
+BRAF,FAM131B-BRAF Fusion,Likely Oncogenic,Gain-of-function,4
-BRAF,SND1-BRAF Fusion,Oncogenic,Gain-of-function,4
+BRAF,SND1-BRAF Fusion,Oncogenic,Gain-of-function,4
-BRAF,ZKSCAN1-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BRAF,ZKSCAN1-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BRAF,GTF2I-BRAF Fusion,Oncogenic,Likely Gain-of-function,4
+BRAF,GTF2I-BRAF Fusion,Oncogenic,Likely Gain-of-function,4
-BRAF,AKAP9-BRAF Fusion,Oncogenic,Gain-of-function,4
+BRAF,AKAP9-BRAF Fusion,Oncogenic,Gain-of-function,4
-BRAF,PCBP2-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BRAF,PCBP2-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BRAF,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BRAF,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BRAF,MKRN1-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BRAF,MKRN1-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BRAF,AGK-BRAF Fusion,Oncogenic,Gain-of-function,4
+BRAF,AGK-BRAF Fusion,Oncogenic,Gain-of-function,4
-BRAF,KIAA1549-BRAF Fusion,Oncogenic,Gain-of-function,4
+BRAF,KIAA1549-BRAF Fusion,Oncogenic,Gain-of-function,4
-BRAF,CUL1-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BRAF,CUL1-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BRAF,PAPSS1-BRAF Fusion,Likely Oncogenic,Gain-of-function,4
+BRAF,PAPSS1-BRAF Fusion,Likely Oncogenic,Gain-of-function,4
-BRAF,PPFIBP2-BRAF Fusion,Oncogenic,Gain-of-function,4
+BRAF,PPFIBP2-BRAF Fusion,Oncogenic,Gain-of-function,4
-BRAF,AGAP3-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BRAF,AGAP3-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BRAF,ZNF767-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BRAF,ZNF767-BRAF Fusion,Likely Oncogenic,Likely Gain-of-function,4
-TFE3,SFPQ-TFE3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+TFE3,SFPQ-TFE3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-TFE3,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+TFE3,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-TFE3,ASPSCR1-TFE3 Fusion,Oncogenic,Gain-of-function,4
+TFE3,ASPSCR1-TFE3 Fusion,Oncogenic,Gain-of-function,4
-TFE3,PRCC-TFE3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+TFE3,PRCC-TFE3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-TFE3,YAP1-TFE3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+TFE3,YAP1-TFE3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MYBL1,MYBL1¨CNFIB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MYBL1,MYBL1¨CNFIB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BCORL1,BCORL1-ELF4 Fusion,Likely Oncogenic,Likely Loss-of-function,3
+BCORL1,BCORL1-ELF4 Fusion,Likely Oncogenic,Likely Loss-of-function,3
-TRD,Fusion,Likely Oncogenic,Likely Gain-of-function,2
+TRD,Fusion,Likely Oncogenic,Likely Gain-of-function,2
-CIC,CIC-DUX4 Fusion,Likely Oncogenic,Likely Loss-of-function,4
+CIC,CIC-DUX4 Fusion,Likely Oncogenic,Likely Loss-of-function,4
-CIC,Fusion,Likely Oncogenic,Likely Loss-of-function,4
+CIC,Fusion,Likely Oncogenic,Likely Loss-of-function,4
-ERBB4,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ERBB4,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ERBB4,EZR-ERBB4 Fusion,Oncogenic,Gain-of-function,4
+ERBB4,EZR-ERBB4 Fusion,Oncogenic,Gain-of-function,4
-WT1,EWSR1-WT1 Fusion,Oncogenic,Gain-of-function,4
+WT1,EWSR1-WT1 Fusion,Oncogenic,Gain-of-function,4
-NTRK3,BTBD1-NTRK3 Fusion,Oncogenic,Gain-of-function,4
+NTRK3,BTBD1-NTRK3 Fusion,Oncogenic,Gain-of-function,4
-NTRK3,EML4-NTRK3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NTRK3,EML4-NTRK3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NTRK3,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NTRK3,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NTRK3,ETV6-NTRK3 Fusion,Oncogenic,Gain-of-function,4
+NTRK3,ETV6-NTRK3 Fusion,Oncogenic,Gain-of-function,4
-NTRK3,KANK1-NTRK3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NTRK3,KANK1-NTRK3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NTRK3,UBE2R2-NTRK3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NTRK3,UBE2R2-NTRK3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NTRK3,HNRNPA2B1- NTRK3 Fusion,Inconclusive,Inconclusive,4
+NTRK3,HNRNPA2B1- NTRK3 Fusion,Inconclusive,Inconclusive,4
-NR4A3,EWSR1-NR4A3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NR4A3,EWSR1-NR4A3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BCL9,MEF2D-BCL9 Fusion,Oncogenic,Likely Gain-of-function,4
+BCL9,MEF2D-BCL9 Fusion,Oncogenic,Likely Gain-of-function,4
-BCL9,BCL9-IGH Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BCL9,BCL9-IGH Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BCL9,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BCL9,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-TRA,Fusion,Likely Oncogenic,Likely Gain-of-function,2
+TRA,Fusion,Likely Oncogenic,Likely Gain-of-function,2
-RBM15,RBM15-MRTFA Fusion,Oncogenic,Gain-of-function,4
+RBM15,RBM15-MRTFA Fusion,Oncogenic,Gain-of-function,4
-MYCL,RLF-MYCL Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MYCL,RLF-MYCL Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BCL10,IGH-BCL10 Fusion,Oncogenic,Gain-of-function,4
+BCL10,IGH-BCL10 Fusion,Oncogenic,Gain-of-function,4
-MAFB,IGH-MAFB Fusion,Oncogenic,Gain-of-function,4
+MAFB,IGH-MAFB Fusion,Oncogenic,Gain-of-function,4
-NTRK2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NTRK2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NTRK2,ETV6-NTRK2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NTRK2,ETV6-NTRK2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NKX2-1,TRA-NKX2-1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NKX2-1,TRA-NKX2-1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NKX2-1,TRB-NKX2-1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NKX2-1,TRB-NKX2-1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NKX2-1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NKX2-1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NKX2-1,IGH-NKX2-1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NKX2-1,IGH-NKX2-1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-TP63,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+TP63,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-TRB,Fusion,Likely Oncogenic,Likely Gain-of-function,2
+TRB,Fusion,Likely Oncogenic,Likely Gain-of-function,2
-ETV1,TMPRSS2-ETV1 Fusion,Oncogenic,Gain-of-function,4
+ETV1,TMPRSS2-ETV1 Fusion,Oncogenic,Gain-of-function,4
-ETV1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ETV1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ETV1,EWSR1-ETV1 Fusion,Oncogenic,Gain-of-function,4
+ETV1,EWSR1-ETV1 Fusion,Oncogenic,Gain-of-function,4
-ROS1,FIG-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ROS1,FIG-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ROS1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ROS1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ROS1,TPM3-ROS1 Fusion,Oncogenic,Gain-of-function,4
+ROS1,TPM3-ROS1 Fusion,Oncogenic,Gain-of-function,4
-ROS1,CCDC6-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ROS1,CCDC6-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ROS1,KDELR2-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ROS1,KDELR2-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ROS1,CEP85L-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ROS1,CEP85L-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ROS1,YWHAE-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ROS1,YWHAE-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ROS1,GOPC-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ROS1,GOPC-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ROS1,CD74-ROS1 Fusion,Oncogenic,Gain-of-function,4
+ROS1,CD74-ROS1 Fusion,Oncogenic,Gain-of-function,4
-ROS1,EZR-ROS1 Fusion,Oncogenic,Gain-of-function,4
+ROS1,EZR-ROS1 Fusion,Oncogenic,Gain-of-function,4
-ROS1,LIMA1-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ROS1,LIMA1-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ROS1,SDC4-ROS1 Fusion,Oncogenic,Gain-of-function,4
+ROS1,SDC4-ROS1 Fusion,Oncogenic,Gain-of-function,4
-ROS1,MSN-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ROS1,MSN-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ROS1,LRIG3-ROS1 Fusion,Oncogenic,Gain-of-function,4
+ROS1,LRIG3-ROS1 Fusion,Oncogenic,Gain-of-function,4
-ROS1,TFG-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ROS1,TFG-ROS1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ROS1,SLC34A2-ROS1 Fusion,Oncogenic,Gain-of-function,4
+ROS1,SLC34A2-ROS1 Fusion,Oncogenic,Gain-of-function,4
-NTRK1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NTRK1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NTRK1,CD74-NTRK1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NTRK1,CD74-NTRK1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NTRK1,TFG-NTRK1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NTRK1,TFG-NTRK1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NTRK1,EPS15-NTRK1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NTRK1,EPS15-NTRK1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NTRK1,MPRIP-NTRK1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NTRK1,MPRIP-NTRK1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NTRK1,TPR-NTRK1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NTRK1,TPR-NTRK1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NTRK1,LMNA-NTRK1 Fusion,Oncogenic,Gain-of-function,4
+NTRK1,LMNA-NTRK1 Fusion,Oncogenic,Gain-of-function,4
-NTRK1,NFASC-NTRK1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NTRK1,NFASC-NTRK1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-RARA,BCOR-RARA Fusion,Likely Oncogenic,Likely Gain-of-function,4
+RARA,BCOR-RARA Fusion,Likely Oncogenic,Likely Gain-of-function,4
-RARA,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+RARA,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-RARA,PML-RARA Fusion,Oncogenic,Likely Gain-of-function,4
+RARA,PML-RARA Fusion,Oncogenic,Likely Gain-of-function,4
-RARA,GTF2I-RARA Fusion,Likely Oncogenic,Likely Gain-of-function,4
+RARA,GTF2I-RARA Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BCL6,IGH-BCL6 Fusion,Oncogenic,Gain-of-function,4
+BCL6,IGH-BCL6 Fusion,Oncogenic,Gain-of-function,4
-BCL6,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BCL6,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-NUP98,NUP98-NSD1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NUP98,NUP98-NSD1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-CCND3,IGH-CCND3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+CCND3,IGH-CCND3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-TAL1,SIL-TAL1 Fusion,Oncogenic,Gain-of-function,4
+TAL1,SIL-TAL1 Fusion,Oncogenic,Gain-of-function,4
-TAL1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+TAL1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PIK3CB,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PIK3CB,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PIK3CB,ACPP-PIK3CB Fusion,Likely Oncogenic,Likely Gain-of-function,4
+PIK3CB,ACPP-PIK3CB Fusion,Likely Oncogenic,Likely Gain-of-function,4
-RAF1,ATG7-RAF1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+RAF1,ATG7-RAF1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-RAF1,GOLGA4-RAF1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+RAF1,GOLGA4-RAF1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-RAF1,SRGAP3-RAF1 Fusion,Oncogenic,Gain-of-function,4
+RAF1,SRGAP3-RAF1 Fusion,Oncogenic,Gain-of-function,4
-RAF1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+RAF1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-RAF1,ESRP1-RAF1 Fusion,Oncogenic,Gain-of-function,4
+RAF1,ESRP1-RAF1 Fusion,Oncogenic,Gain-of-function,4
-RAF1,QKI-RAF1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+RAF1,QKI-RAF1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PDGFB,COL1A1-PDGFB Fusion,Oncogenic,Gain-of-function,4
+PDGFB,COL1A1-PDGFB Fusion,Oncogenic,Gain-of-function,4
-TET1,MLL-TET1 Fusion,Oncogenic,Gain-of-function,4
+TET1,MLL-TET1 Fusion,Oncogenic,Gain-of-function,4
-NUTM1,BRD4-NUTM1 Fusion,Oncogenic,Gain-of-function,4
+NUTM1,BRD4-NUTM1 Fusion,Oncogenic,Gain-of-function,4
-CCND1,IGH-CCND1 Fusion,Likely Oncogenic,Gain-of-function,4
+CCND1,IGH-CCND1 Fusion,Likely Oncogenic,Gain-of-function,4
-INSR,SLC12A2-INSR Fusion,Likely Oncogenic,Likely Gain-of-function,4
+INSR,SLC12A2-INSR Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ESR1,ESR1-SOX9 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ESR1,ESR1-SOX9 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ESR1,ESR1-YAP1 Fusion,Oncogenic,Gain-of-function,4
+ESR1,ESR1-YAP1 Fusion,Oncogenic,Gain-of-function,4
-ESR1,ESR1-GYG1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ESR1,ESR1-GYG1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ESR1,ESR1-DAB2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ESR1,ESR1-DAB2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ESR1,ESR1-CCDC170 Fusion,Oncogenic,Gain-of-function,4
+ESR1,ESR1-CCDC170 Fusion,Oncogenic,Gain-of-function,4
-ESR1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ESR1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-CREBBP,KAT6A-CREBBP Fusion,Likely Oncogenic,Likely Gain-of-function,4
+CREBBP,KAT6A-CREBBP Fusion,Likely Oncogenic,Likely Gain-of-function,4
-LMO2,Fusion,Oncogenic,Gain-of-function,4
+LMO2,Fusion,Oncogenic,Gain-of-function,4
-MALT1,IGH-MALT1 Fusion,Inconclusive,Inconclusive,4
+MALT1,IGH-MALT1 Fusion,Inconclusive,Inconclusive,4
-MALT1,BIRC3-MALT1 Fusion,Oncogenic,Gain-of-function,4
+MALT1,BIRC3-MALT1 Fusion,Oncogenic,Gain-of-function,4
-ERG,EWSR1-ERG Fusion,Oncogenic,Gain-of-function,4
+ERG,EWSR1-ERG Fusion,Oncogenic,Gain-of-function,4
-ERG,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ERG,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-ERG,FUS-ERG Fusion,Oncogenic,Gain-of-function,4
+ERG,FUS-ERG Fusion,Oncogenic,Gain-of-function,4
-ERG,TMPRSS2-ERG Fusion,Oncogenic,Gain-of-function,4
+ERG,TMPRSS2-ERG Fusion,Oncogenic,Gain-of-function,4
-GATA1,MYB-GATA1 Fusion,Oncogenic,Gain-of-function,4
+GATA1,MYB-GATA1 Fusion,Oncogenic,Gain-of-function,4
-ATXN7,RAD51C-ATXN7 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ATXN7,RAD51C-ATXN7 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-RET,RUFY1-RET Fusion,Likely Oncogenic,Likely Gain-of-function,4
+RET,RUFY1-RET Fusion,Likely Oncogenic,Likely Gain-of-function,4
-RET,EML4-RET Fusion,Likely Oncogenic,Likely Gain-of-function,4
+RET,EML4-RET Fusion,Likely Oncogenic,Likely Gain-of-function,4
-RET,MYH10-RET fusion,Likely Oncogenic,Likely Gain-of-function,4
+RET,MYH10-RET fusion,Likely Oncogenic,Likely Gain-of-function,4
-RET,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+RET,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-RET,KIF5B-RET Fusion,Oncogenic,Gain-of-function,4
+RET,KIF5B-RET Fusion,Oncogenic,Gain-of-function,4
-RET,TRIM27-RET Fusion,Likely Oncogenic,Likely Gain-of-function,4
+RET,TRIM27-RET Fusion,Likely Oncogenic,Likely Gain-of-function,4
-RET,RET-SEPTIN9 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+RET,RET-SEPTIN9 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-RET,SPECC1L-RET fusion,Likely Oncogenic,Likely Gain-of-function,4
+RET,SPECC1L-RET fusion,Likely Oncogenic,Likely Gain-of-function,4
-RET,NCOA4-RET Fusion,Oncogenic,Gain-of-function,4
+RET,NCOA4-RET Fusion,Oncogenic,Gain-of-function,4
-RET,CCDC6-RET Fusion,Oncogenic,Gain-of-function,4
+RET,CCDC6-RET Fusion,Oncogenic,Gain-of-function,4
-WIF1,HMGA2-WIF1 Fusion,Inconclusive,Inconclusive,4
+WIF1,HMGA2-WIF1 Fusion,Inconclusive,Inconclusive,4
-JAK2,PCM1-JAK2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+JAK2,PCM1-JAK2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-JAK2,BCR-JAK2 Fusion,Oncogenic,Gain-of-function,4
+JAK2,BCR-JAK2 Fusion,Oncogenic,Gain-of-function,4
-JAK2,TEL-JAK2 Fusion,Oncogenic,Gain-of-function,4
+JAK2,TEL-JAK2 Fusion,Oncogenic,Gain-of-function,4
-JAK2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+JAK2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-JAK2,ATF7IP-JAK2 Fusion,Oncogenic,Gain-of-function,4
+JAK2,ATF7IP-JAK2 Fusion,Oncogenic,Gain-of-function,4
-JAK2,PAX5-JAK2 Fusion,Oncogenic,Gain-of-function,4
+JAK2,PAX5-JAK2 Fusion,Oncogenic,Gain-of-function,4
-MET,PTPRZ1-MET Fusion,Oncogenic,Gain-of-function,4
+MET,PTPRZ1-MET Fusion,Oncogenic,Gain-of-function,4
-MET,HLA-DRB1-MET Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MET,HLA-DRB1-MET Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MET,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MET,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MET,CCDC6-MET Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MET,CCDC6-MET Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MET,CD74-MET Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MET,CD74-MET Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MET,CLIP2-MET Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MET,CLIP2-MET Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MET,EPHB4-MET Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MET,EPHB4-MET Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MET,TFG-MET Fusion,Oncogenic,Gain-of-function,4
+MET,TFG-MET Fusion,Oncogenic,Gain-of-function,4
-MET,KIF5B-MET Fusion,Oncogenic,Gain-of-function,4
+MET,KIF5B-MET Fusion,Oncogenic,Gain-of-function,4
-MET,MET-DST Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MET,MET-DST Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MET,STARD3NL-MET Fusion,Oncogenic,Gain-of-function,4
+MET,STARD3NL-MET Fusion,Oncogenic,Gain-of-function,4
-MET,CD47-MET Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MET,CD47-MET Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FUS,FUS-CREB3L2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FUS,FUS-CREB3L2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FUS,FUS-CHOP Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FUS,FUS-CHOP Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FUS,FUS-ERG Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FUS,FUS-ERG Fusion,Likely Oncogenic,Likely Gain-of-function,4
-DUSP22,Fusion,Likely Oncogenic,Likely Loss-of-function,4
+DUSP22,Fusion,Likely Oncogenic,Likely Loss-of-function,4
-YAP1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+YAP1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-YAP1,YAP1-MAMLD1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+YAP1,YAP1-MAMLD1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-YAP1,YAP1-FAM118B Fusion,Likely Oncogenic,Likely Gain-of-function,4
+YAP1,YAP1-FAM118B Fusion,Likely Oncogenic,Likely Gain-of-function,4
-YAP1,YAP1-SS18 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+YAP1,YAP1-SS18 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-YAP1,YAP1-TFE3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+YAP1,YAP1-TFE3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-CRLF2,P2RY8-CRLF2 Fusion,Oncogenic,Gain-of-function,4
+CRLF2,P2RY8-CRLF2 Fusion,Oncogenic,Gain-of-function,4
-CRLF2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+CRLF2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-CRLF2,IGH-CRLF2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+CRLF2,IGH-CRLF2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-LTK,CLIP1-LTK fusion,Likely Oncogenic,Likely Gain-of-function,4
+LTK,CLIP1-LTK fusion,Likely Oncogenic,Likely Gain-of-function,4
-BCL3,IGH-BCL3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BCL3,IGH-BCL3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-CREB1,EWSR1-CREB1 Fusion,Inconclusive,Inconclusive,4
+CREB1,EWSR1-CREB1 Fusion,Inconclusive,Inconclusive,4
-ATF1,EWSR1-ATF1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+ATF1,EWSR1-ATF1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BCL2,IGH-BCL2 Fusion,Oncogenic,Gain-of-function,4
+BCL2,IGH-BCL2 Fusion,Oncogenic,Gain-of-function,4
-BCL2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BCL2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FOXO1,PAX7-FOXO1 Fusion,Inconclusive,Inconclusive,4
+FOXO1,PAX7-FOXO1 Fusion,Inconclusive,Inconclusive,4
-TYK2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+TYK2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PPARG,PAX8-PPARG Fusion,Oncogenic,Gain-of-function,4
+PPARG,PAX8-PPARG Fusion,Oncogenic,Gain-of-function,4
-MEF2D,MEF2D-SS18 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MEF2D,MEF2D-SS18 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MEF2D,MEF2D-HNRNPUL1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MEF2D,MEF2D-HNRNPUL1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MEF2D,MEF2D-DAZAP1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MEF2D,MEF2D-DAZAP1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MEF2D,MEF2D-CSF1R Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MEF2D,MEF2D-CSF1R Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MEF2D,MEF2D-FOXJ2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MEF2D,MEF2D-FOXJ2 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-PRKACA,DNAJB1-PRKACA Fusion,Oncogenic,Gain-of-function,4
+PRKACA,DNAJB1-PRKACA Fusion,Oncogenic,Gain-of-function,4
-IRF4,DUSP22-IRF4 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+IRF4,DUSP22-IRF4 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-IRF4,IGH-IRF4 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+IRF4,IGH-IRF4 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-IRF4,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+IRF4,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-TCF3,TCF3-PBX1 Fusion,Oncogenic,Gain-of-function,4
+TCF3,TCF3-PBX1 Fusion,Oncogenic,Gain-of-function,4
-TCF3,TCF3-HLF Fusion,Oncogenic,Gain-of-function,4
+TCF3,TCF3-HLF Fusion,Oncogenic,Gain-of-function,4
-SET,SET-NUP214 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+SET,SET-NUP214 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-BRD4,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+BRD4,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FLI1,EWSR1-FLI1 Fusion,Oncogenic,Gain-of-function,4
+FLI1,EWSR1-FLI1 Fusion,Oncogenic,Gain-of-function,4
-KMT2A,KMT2A-MLLT1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+KMT2A,KMT2A-MLLT1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-KMT2A,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+KMT2A,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-KMT2A,KMT2A-MLLT3 Fusion,Oncogenic,Gain-of-function,4
+KMT2A,KMT2A-MLLT3 Fusion,Oncogenic,Gain-of-function,4
-RUNX1,Fusion,Likely Oncogenic,Likely Loss-of-function,4
+RUNX1,Fusion,Likely Oncogenic,Likely Loss-of-function,4
-RUNX1,ETV6-RUNX1 Fusion,Oncogenic,Likely Switch-of-function,4
+RUNX1,ETV6-RUNX1 Fusion,Oncogenic,Likely Switch-of-function,4
-RUNX1,RUNX1-RUNX1T1 Fusion,Likely Oncogenic,Loss-of-function,4
+RUNX1,RUNX1-RUNX1T1 Fusion,Likely Oncogenic,Loss-of-function,4
-RUNX1,RUNX1-EVI1 Fusion,Likely Oncogenic,Loss-of-function,4
+RUNX1,RUNX1-EVI1 Fusion,Likely Oncogenic,Loss-of-function,4
-CCNB3,BCOR-CCNB3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+CCNB3,BCOR-CCNB3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-AKT1,LAMTOR1-AKT1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+AKT1,LAMTOR1-AKT1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-HMGA1,TBL1XR1-HMGA1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+HMGA1,TBL1XR1-HMGA1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-EWSR1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+EWSR1,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-FOXP1,IGH-FOXP1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+FOXP1,IGH-FOXP1 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-AKT2,BCAM-AKT2 Fusion,Likely Oncogenic,Gain-of-function,4
+AKT2,BCAM-AKT2 Fusion,Likely Oncogenic,Gain-of-function,4
-AKT2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+AKT2,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-HMGA2,HMGA2-LPP Fusion,Likely Oncogenic,Likely Gain-of-function,4
+HMGA2,HMGA2-LPP Fusion,Likely Oncogenic,Likely Gain-of-function,4
-CSF1R,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+CSF1R,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-CSF1R,RBM6-CSF1R Fusion,Likely Oncogenic,Likely Gain-of-function,4
+CSF1R,RBM6-CSF1R Fusion,Likely Oncogenic,Likely Gain-of-function,4
-DEK,DEK-NUP214 Fusion,Oncogenic,Gain-of-function,4
+DEK,DEK-NUP214 Fusion,Oncogenic,Gain-of-function,4
-AKT3,MAGI3-AKT3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+AKT3,MAGI3-AKT3 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-AKT3,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+AKT3,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MLLT10,KMT2A-MLLT10 Fusion,Oncogenic,Gain-of-function,4
+MLLT10,KMT2A-MLLT10 Fusion,Oncogenic,Gain-of-function,4
-MLLT10,Fusion,Likely Oncogenic,Likely Gain-of-function,4
+MLLT10,Fusion,Likely Oncogenic,Likely Gain-of-function,4
-MLLT10,PICALM-MLLT10 Fusion,Oncogenic,Gain-of-function,4
+MLLT10,PICALM-MLLT10 Fusion,Oncogenic,Gain-of-function,4
-EP300,EP300-MOZ Fusion,Likely Oncogenic,Gain-of-function,3
+EP300,EP300-MOZ Fusion,Likely Oncogenic,Gain-of-function,3
-EP300,EP300-MLL Fusion,Likely Oncogenic,Gain-of-function,5
+EP300,EP300-MLL Fusion,Likely Oncogenic,Gain-of-function,5
-FGFR1,FGFR1-TACC1 Fusion,Oncogenic,Gain-of-function,2
+FGFR1,FGFR1-TACC1 Fusion,Oncogenic,Gain-of-function,2
-FGFR1,FGFR1OP1-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,5
+FGFR1,FGFR1OP1-FGFR1 Fusion,Likely Oncogenic,Gain-of-function,5
-ALK,NPM-ALK Fusion,Oncogenic,Gain-of-function,3
+ALK,NPM-ALK Fusion,Oncogenic,Gain-of-function,3
-NOTCH1,SEC16A1-NOTCH1 Fusion,Oncogenic,Gain-of-function,1
+NOTCH1,SEC16A1-NOTCH1 Fusion,Oncogenic,Gain-of-function,1
-NUP98,NSD1-NUP98 Fusion,Likely Oncogenic,Likely Gain-of-function,4
+NUP98,NSD1-NUP98 Fusion,Likely Oncogenic,Likely Gain-of-function,4
-GTF2I,Fusion,Likely Oncogenic,Likely Gain-of-function,2
+GTF2I,Fusion,Likely Oncogenic,Likely Gain-of-function,2
-NRG1,SDC4-NRG1 Fusion,Likely Oncogenic,Likely Gain-of-function,
+NRG1,SDC4-NRG1 Fusion,Likely Oncogenic,Likely Gain-of-function,
-YY1,EWSR1-YY1 Fusion,Inconclusive,Inconclusive,1
+YY1,EWSR1-YY1 Fusion,Inconclusive,Inconclusive,1
+TMPRSS2,TMPRSS2-ALPL Fusion,Resistance,Inconclusive,1

database/oncotree.cancertype.20230801.txt

@@ -635,9 +635,27 @@ ST2101	SOLID-LUNG-LNET	Lung Neuroendocrine Tumor	肺部神经内分泌肿瘤	Non
 ST210101	SOLID-LUNG-LNET-SCLC	Small Cell Lung Cancer	小细胞肺癌	Small Cell Lung Cancer	小细胞肺癌
 ST210102	SOLID-LUNG-LNET-LUNE	Large Cell Neuroendocrine Carcinoma	大细胞神经内分泌癌	Non-Small Cell Lung Cancer	非小细胞肺癌
 ST210103	SOLID-LUNG-LNET-LUCA	Lung Carcinoid	肺类癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST21010301	SOLID-LUNG-LNET-LUCA-ALUCA	Atypical Lung Carcinoid	肺非典型类癌	Non-Small Cell Lung Cancer	非小细胞肺癌
 ST210104	SOLID-LUNG-LNET-ALUCA	Atypical Lung Carcinoid	肺非典型类癌	Non-Small Cell Lung Cancer	非小细胞肺癌
-ST2102	SOLID-LUNG-PPB	Pleuropulmonary Blastoma	胸膜肺母细胞瘤	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST21010101	SOLID-LUNG-LNET-SCLC-CSCLC	Combined Small Cell Lung Carcinoma	复合性小细胞癌	Small Cell Lung Cancer	小细胞肺癌
-ST2103	SOLID-LUNG-NSCLC	Non-Small Cell Lung Cancer	非小细胞肺癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2102	SOLID-LUNG-NSCLC	Non-Small Cell Lung Cancer	非小细胞肺癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST210201	SOLID-LUNG-NSCLC-NSNSCLC	Lung Non-Squamous Non-Small Cell Carcinoma	非鳞状非小细胞肺癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST21020101	SOLID-LUNG-NSCLC-NSNSCLC-CMPT	Ciliated Muconodular Papillary Tumor of the Lung	肺纤毛黏液结节性乳头状肿瘤	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST21020102	SOLID-LUNG-NSCLC-NSNSCLC-LUAS	Lung Adenosquamous Carcinoma	肺腺鳞癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST21020103	SOLID-LUNG-NSCLC-NSNSCLC-LCLC	Large Cell Lung Carcinoma	大细胞肺癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2102010301	SOLID-LUNG-NSCLC-NSNSCLC-LCLC-CCLC	Clear Cell Carcinoma of the Lung	肺透明细胞癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2102010302	SOLID-LUNG-NSCLC-NSNSCLC-LCLC-GCLC	Giant Cell Carcinoma of the Lung	肺巨细胞癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2102010303	SOLID-LUNG-NSCLC-NSNSCLC-LCLC-BLCLC	Basaloid Large Cell Carcinoma of the Lung	肺基底细胞样大细胞癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2102010304	SOLID-LUNG-NSCLC-NSNSCLC-LCLC-LECLC	Lymphoepithelioma-like Carcinoma of the Lung	肺淋巴上皮瘤样癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2102010305	SOLID-LUNG-NSCLC-NSNSCLC-LCLC-RLCLC	Large Cell Lung Carcinoma With Rhabdoid Phenotype	伴横纹肌样表型的大细胞肺癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST21020104	SOLID-LUNG-NSCLC-NSNSCLC-NSCLCPD	Poorly Differentiated Non-Small Cell Lung Cancer	低分化非小细胞肺癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST21020105	SOLID-LUNG-NSCLC-NSNSCLC-LUAD	Lung Adenocarcinoma	肺腺癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2102010501	SOLID-LUNG-NSCLC-NSNSCLC-LUAD-LAIS	Lung Adenocarcinoma In Situ	原位肺腺癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST21020106	SOLID-LUNG-NSCLC-NSNSCLC-SARCL	Sarcomatoid Carcinoma of the Lung	肺肉瘤样癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2102010601	SOLID-LUNG-NSCLC-NSNSCLC-SARCL-SPCC	Spindle Cell Carcinoma of the Lung	肺梭形细胞癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2102010602	SOLID-LUNG-NSCLC-NSNSCLC-SARCL-LUPC	Pleomorphic Carcinoma of the Lung	肺多形性癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST210202	SOLID-LUNG-NSCLC-LUSC	Lung Squamous Cell Carcinoma	肺鳞状细胞癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2103	SOLID-LUNG-NUTCL	NUT Carcinoma of the Lung	肺NUT癌	Non-Small Cell Lung Cancer	非小细胞肺癌
 ST210301	SOLID-LUNG-NSCLC-CMPT	Ciliated Muconodular Papillary Tumor of the Lung	肺纤毛黏液结节性乳头状肿瘤	Non-Small Cell Lung Cancer	非小细胞肺癌
 ST210302	SOLID-LUNG-NSCLC-NUTCL	NUT Carcinoma of the Lung	肺NUT癌	Non-Small Cell Lung Cancer	非小细胞肺癌
 ST210303	SOLID-LUNG-NSCLC-NSCLCPD	Poorly Differentiated Non-Small Cell Lung Cancer	低分化非小细胞肺癌	Non-Small Cell Lung Cancer	非小细胞肺癌
@@ -655,10 +673,12 @@ ST21030804	SOLID-LUNG-NSCLC-LCLC-LECLC	Lymphoepithelioma-like Carcinoma of the L
 ST21030805	SOLID-LUNG-NSCLC-LCLC-RLCLC	Large Cell Lung Carcinoma With Rhabdoid Phenotype	伴横纹肌样表型的大细胞肺癌	Non-Small Cell Lung Cancer	非小细胞肺癌
 ST210309	SOLID-LUNG-NSCLC-LUAD	Lung Adenocarcinoma	肺腺癌	Non-Small Cell Lung Cancer	非小细胞肺癌
 ST210310	SOLID-LUNG-NSCLC-LUPC	Pleomorphic Carcinoma of the Lung	肺多形性癌	Non-Small Cell Lung Cancer	非小细胞肺癌
-ST2104	SOLID-LUNG-LAM	Pulmonary Lymphangiomyomatosis	肺淋巴管肌瘤病	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2104	SOLID-LUNG-SGTTL	Salivary Gland-Type Tumor of the Lung	肺涎腺型肿瘤	Non-Small Cell Lung Cancer	非小细胞肺癌
-ST2105	SOLID-LUNG-LAIS	Lung Adenocarcinoma In Situ	原位肺腺癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST210401	SOLID-LUNG-SGTTL-LUMEC	Mucoepidermoid Carcinoma of the Lung	肺黏液表皮样癌	Non-Small Cell Lung Cancer	非小细胞肺癌
-ST2106	SOLID-LUNG-CSCLC	Combined Small Cell Lung Carcinoma	复合性小细胞癌	Small Cell Lung Cancer	小细胞肺癌
+ST210402	SOLID-LUNG-SGTTL-LUACC	Adenoid Cystic Carcinoma of the Lung	肺腺腺样囊性癌	Non-Small Cell Lung Cancer	非小细胞肺癌
-ST2107	SOLID-LUNG-SARCL	Sarcomatoid Carcinoma of the Lung	肺肉瘤样癌	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2105	SOLID-LUNG-PPB	Pleuropulmonary Blastoma	胸膜肺母细胞瘤	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2106	SOLID-LUNG-LAM	Pulmonary Lymphangiomyomatosis	肺淋巴管肌瘤病	Non-Small Cell Lung Cancer	非小细胞肺癌
+ST2107	SOLID-LUNG-IMTL	Inflammatory Myofibroblastic Lung Tumor	肺炎性肌纤维母细胞瘤	Non-Small Cell Lung Cancer	非小细胞肺癌
 ST2108	SOLID-LUNG-IMTL	Inflammatory Myofibroblastic Lung Tumor	肺炎性肌纤维母细胞瘤	Non-Small Cell Lung Cancer	非小细胞肺癌
 ST22	SOLID-PENIS	Penile Cancer	阴茎癌	Penile Cancer	阴茎癌
 ST2201	SOLID-PENIS-PSCC	Penile Squamous Cell Carcinoma	阴茎鳞状细胞癌	Penile Cancer	阴茎癌